For more than a decade environmental specimen banking (ESB) has been an established approach for monitoring and retrospective environmental survey purposes in a number of developed countries. Specimen banking is carried out on regional or national scales for various environmental materials. The ecological or problem-oriented approach, as pursued e.g. in Germany or USA has the advantages of a restricted survey and a clear political mandate. Environmental problems, however, are by no means national or regional issues, since the diversity and dispersion of hazardous substances make environmental monitoring clearly a global affair. The structuring of our environment suggests that banking should not be limited by national boundaries, but rather be based on eco-systematic principles. Such distinct banking efforts should be devoted to the monitoring of physico-chemical aspects of climatic change and air pollution, soil quality, and aquatic monitoring on a world-wide scale. As some experience already exists with specialized banking programs for marine samples, such as the National Marine Mammal Tissue Bank or the Mussel Watch Program in the United States, an international marine specimen bank, based on principles of national ESB's, is advocated to be established in due time. Following the recommendations of the 1992 Rio 'Earth Summit' to pursue sustainable development strategies, such an establishment could strongly facilitate efforts concerning pollution control and mitigation, overexploitation and mining of ocean resources on a regional or global scale.
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http://dx.doi.org/10.1016/s0045-6535(97)00061-1 | DOI Listing |
Sci Rep
January 2025
Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany.
Loss of kidney function is a substantial personal and public health burden. Kidney function is typically assessed as estimated glomerular filtration rate (eGFR) based on serum creatinine. UK Biobank provides serum creatinine measurements from study center assessments (SC, n = 425,147 baseline, n = 15,314 with follow-up) and emerging electronic Medical Records (eMR, "GP-clinical") present a promising resource to augment this data longitudinally.
View Article and Find Full Text PDFGenes (Basel)
December 2024
Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, 17671 Athens, Greece.
Background: Metabolic dysfunction-associated steatotic liver disease (MASLD) is the leading cause of liver-related morbidity and mortality. Although the invasive liver biopsy remains the golden standard for MASLD diagnosis, Magnetic Resonance Imaging-derived Proton Density Fat Fraction (MRI-PDFF) is an accurate, non-invasive method for the assessment of treatment response. This study aimed at developing a Polygenic Risk Score (PRS) to improve MRI-PDFF prediction using UK Biobank data to assess an individual's genetic liability to MASLD.
View Article and Find Full Text PDFBiomolecules
January 2025
Department of Surgery and Specialties, Central University Hospital of Asturias, Faculty of Medicine and Health Sciences, University of Oviedo, 33011 Oviedo, Spain.
The aim of the circular economy is to treat waste as a valuable raw material, reintegrating it into the industrial economy and extending the lifecycle of subsequent products. Efforts to reduce the production of hard-to-recycle waste are becoming increasingly important to manufacturers, not only of consumer goods but also of specialized items that are difficult to manufacture, such as medical supplies, which have now become a priority for the European Union. The purpose of the study is to manufacture a novel human-purified type I collagen membrane from bone remnants typically discarded during the processing of cortico-cancellous bones in tissue banks and to evaluate its mechanical properties and effectiveness in regenerating bone-critical mandibular defects in rabbits.
View Article and Find Full Text PDFBMC Public Health
January 2025
Department of Obstetrics and Gynecology, the First Affiliated Hospital of Harbin Medical University, 23 Postal Street, Harbin, 150081, Heilongjiang, P. R. China.
Objective: Little is known about the role of timing of physical activity in female reproductive disorders. These disorders include polycystic ovary syndrome (PCOS), heavy menstrual bleeding (HMB), endometriosis, infertility, and pregnancy-related disorders. This study aims to investigate the associations of activity patterns with female reproductive diseases.
View Article and Find Full Text PDFJ Psychiatry Neurosci
January 2025
From the Department of Neurology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China (Qiao, Zhao, Cong, Y. Li, Tian, Yang, Cao, Su); the School of Electrical and Information Engineering, Zhengzhou University of Light Industry, Zhengzhou, China (Zhu); the Department of Medical Imaging, Henan Provincial People's Hospital & Zhengzhou University People's Hospital, Zhengzhou, China (P. Li).
Background: White matter damage is closely associated with cognitive and psychiatric symptoms and is prevalent in cerebral small vessel disease (CSVD); although the pathophysiological mechanisms involved in CSVD remain elusive, inflammation plays a crucial role. We sought to investigate the relationship between systemic inflammation markers and imaging markers of CVSD, namely white matter hyperintensity (WMH) and microstructural injury.
Methods: We conducted a study involving both cross-sectional and longitudinal data from the UK Biobank Cohort.
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