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The role of recombinant LH in ovarian stimulation: what's new?
Reprod Biol Endocrinol
March 2025
The Fertility Clinic, Skive Regional Hospital, Faculty of Health, Aarhus University, Skive, Denmark.
It is widely recognized that luteinizing hormone (LH) activity is pivotal during folliculogenesis. Nonetheless, the use of LH during ovarian stimulation remains a matter of debate. Indeed, women with good LH function are able to sustain follicle growth and maturation during ovarian stimulation carried out with regimens based on follicle-stimulating hormone (FSH) alone.
View Article and Find Full Text PDFPerformance evolution of the Nano Boron nitride enhanced bone cement composites.
J Orthop Surg Res
March 2025
Department of Orthopaedics, Lanzhou University Second Hospital, Lanzhou, China.
Bone cement is a research hotspot and has been partially applied in the field of bone repair thanks to the good mechanical, physical and antibacterial properties. However, the easy wear and high temperature during curing characteristics would cause surrounding tissue necrosis, which seriously limits the wider application to some extent. In this work, the hexagonal boron nitride (h-BN) nano flakes were optimized to enhance the bone cement matrix (PMMA) via mechanical doping.
View Article and Find Full Text PDF: What's wrong with AlphaFold's score and how to fix it.
bioRxiv
February 2025
Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, PA 19111 USA.
AlphaFold's metric is used to predict the accuracy of structural predictions of protein-protein interactions (PPIs) and the probability that two proteins interact. Many AF2/AF3 users have experienced the phenomenon that if they trim full-length sequence constructs (e.g.
View Article and Find Full Text PDFThe nucleation and growth mechanism of spherical Li for advanced Li metal anodes - a review.
Chem Commun (Camb)
February 2025
School of Energy and Power, Jiangsu University of Science and Technology, Zhenjiang 212003, China.
Metallic lithium (Li) is known as the "Holy Grail" of anode materials in the research area of Li-based batteries. However, Li metal anodes (LMAs) are plagued by infinite volume changes and dendrite formation during operation. Spherical Li exhibits rounded surfaces, which effectively mitigates the short circuit risks associated with dendritic Li, and has the smallest specific surface area compared to other deposit morphologies, thus enabling less electrolyte consumption and higher Coulombic efficiency (CE).
View Article and Find Full Text PDFA method of coating life prediction based on high temperature thermal shock life test and three-dimensional heat transfer analysis.
Sci Rep
January 2025
School of Instrumental Science and Engineering, Harbin Institute of Technology, 150001, Harbin, People's Republic of China.
In this study, a method for predicting the thermal shock life of coatings is proposed, and a model for predicting the thermal shock life of coatings based on high temperature thermal shock life test and three-dimensional heat transfer analysis is established. Firstly, the thermal shock life of coatings at different cooling and heating cycle temperatures is obtained through a designed thermal shock life testing device for silicide coatings at a wide-temperature range from 500℃ to 3000℃. Secondly, the actual thickness of the coating and the continuous oxidation in the thermal shock life test are taken into consideration.
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