AI Article Synopsis

  • Population genetic studies focus on genetic variability and comparing distances between populations to infer their evolutionary dynamics.
  • The study found that the estimated number of exchanged individuals per generation (Nm) was consistently greater than 1 across different data sets and methods.
  • The observed correlation between geographic and genetic distances indicates a pattern of isolation by distance, suggesting high gene flow among geographically close human populations.

Article Abstract

Population genetic studies are mainly based on the description of genetic variability and on interpopulational comparisons using genetic distance measures. The evolutionary dynamics of the populations are inferred from these parameters and accurate estimates of gene flow may be critical. The present study reevaluates the role of gene flow in human populations by different statistical methods from a number of microsatellite and protein polymorphism data. The estimated number of individuals exchanged per generation (Nm) was greater than 1 in all data sets with all statistical methods. The correlation between geographic and genetic distances suggests a pattern of isolation by distance, characteristic of demographic and genetic equilibrium conditions among populations worldwide. Thus the high values of Nm may be interpreted as a reflection of high gene flow between geographically close populations. As expected, gene flow appears to exert a pivotal role in the genetic history of humans.

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http://dx.doi.org/10.1159/000154405DOI Listing

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