Personal exposure to solvents was studied among hairdressers in 28 salons in two regions during two seasons in The Netherlands. Ethanol was used as a marker for solvent exposure. Auxiliary data, such as salon and work characteristics, meteorological conditions and information on the presence of control measures, were collected during the measurements. The average exposure to ethanol was almost a factor of 200 below the occupational exposure limit, but differences in average ethanol concentrations up to a factor of 30 were present between salons. Exposure concentrations were significantly higher on Fridays than on other days of the week. Contrary to expectation, exposures were somewhat lower in the spring than in the summer and in an urban than a semi-rural area. An empirical statistical model based on exposure data collected during the first measurement period appeared not to be valid for the encountered circumstances in the second measurement period. An alternative classification scheme based on two easily obtainable salon and task characteristics was elaborated. This scheme will be applied in an ongoing epidemiological study on reproductive disorders among hairdressers and their offspring.
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http://dx.doi.org/10.1016/S0003-4878(96)00040-3 | DOI Listing |
Forensic Sci Med Pathol
January 2025
Department of Forensic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.
Nitrous oxide (NO) abuse is becoming increasingly popular worldwide. Moreover, the use of NO combined with other substances, such as alcohol, is also common. Accidental deaths associated with NO abuse are rare in forensic practice, with most fatal cases involving continuous inhalation equipment or exposure in a confined space.
View Article and Find Full Text PDFAlcohol
January 2025
Department of Neuroscience, The Scripps Research Institute, La Jolla CA 92037. Electronic address:
Disturbance in sleep and activity rhythms are significant health risks associated with alcohol use during adolescence. Many investigators support the theory of a reciprocal relationship between disrupted circadian rhythms, sleep patterns, and alcohol usage. However, in human studies it is difficult to disentangle other factors (i.
View Article and Find Full Text PDFHeliyon
January 2025
Department of Protozoology, Faculty of Tropical Medicine, Mahidol University, Ratchawithi Road, Ratchathewi, Bangkok, 10400, Thailand.
is a major pathogen of the gastrointestinal tract, and infections impact both human health and the economy. The ongoing issues with drug resistance and the side effects of current anti- treatments highlight the urgent need for new therapeutic options. This study focused on investigating the efficacy of crude extracts of from Thailand against .
View Article and Find Full Text PDFAlcohol
January 2025
Department of Neuroscience, Charleston Alcohol Research Center, Medical University of South Carolina, 70 President Street, Drug Discovery Building, Charleston, SC 29425. Electronic address:
Although men have historically exhibited higher levels of alcohol use disorder (AUD) diagnosis, the gap between men and women has been diminishing quickly. Preclinical screening for pharmacological treatments for AUD has typically focused solely on males, ignoring the possibility that males and females may differ mechanistically for the same behavioral phenotype. To ensure the efficacy of treatment targets across the sexes, it is crucial to study the pharmacological effects of AUD treatments in males and females.
View Article and Find Full Text PDFEur J Pharm Sci
January 2025
Sartorius Stedim Biotech GmbH, August-Spindler-Straße 11, 37079 Göttingen ,Germany.
We evaluated algorithms designed to extrapolate extractables data for predicting process equipment-related leachables (PERLs) and assessing PERL exposure in single-use systems (SUSs) and their assemblies. The robustness and sensitivity of these algorithms were tested against variations in input data, including extrapolation algorithms for both short and long contact time extractables data obtained from the standardized extractables protocol provided in USP 〈665〉. Our findings demonstrate that extrapolated data for SUS and assemblies are suitable for safety assessments.
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