Ultrasound in the evaluation of bone fragility caused by osteoporosis: a comparison between different sites of measurement.

The authors compare two different measurement sites of ultrasound transmission velocity (UTV) in discriminating between subjects with or without vertebral fracture caused by osteoporosis. To this purpose a total of 150 women in menopause, of which 50 with vertebral fracture documented radiologically, for whom UTV was measured in the distal radius and in the patella, were examined. In both sites measurement of UTV in fractured women (1531.9 m/sec in the distal radius, and 1825.1 m/sec in the patella) was significantly less than for healthy women (1557.4 m/sec in the distal radius and 1874.5 m/sec in the patella) and there was a significant inverse linear correlation with age. The logistic regression shows that in both sites ultrasound examination is capable of significantly discriminating between osteoporotic women with fracture and those without fracture (odds ratio of the distal radius = 38.857, odds ratio of the patella = 7.822). A comparison of the discriminating capacity of the two measurement sites shows that the ORC curves for the distal radius (area = 0.773) is significantly greater than that of the patella (area = 0.684). Our study confirms that UTV can discriminate healthy subjects from osteoporotic ones, and it shows that the method in question has greater diagnostic sensitivity in the distal radius than in the patella.