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Altered fibrin clot properties and elevated von Willebrand factor are associated with progression to permanent atrial fibrillation: A cohort study.
Eur J Clin Invest
January 2025
Department of Thromboembolic Disorders, Institute of Cardiology, Jagiellonian University Medical College, Krakow, Poland.
Background: The role of a prothrombotic state in atrial fibrillation (AF) progression to permanent arrythmia (PerAF) is unclear. Formation of denser and poorly lysable fibrin clots has been observed in AF patients also with sinus rhythm in association with higher stroke risk. We investigated whether altered fibrin clot properties and other prothrombotic state markers may contribute to AF transition to PerAF.
View Article and Find Full Text PDFAssociation between METTL14 gene polymorphisms and risk of ovarian endometriosis.
Front Genet
January 2025
Department of Gynecology, The Affiliated Guangdong Second Provincial General Hospital of Jinan University, Guangzhou, Guangdong, China.
Background: Endometriosis, a prevalent chronic gynecological condition, is frequently associated with infertility and pelvic pain. Despite numerous studies indicating a correlation between epigenetic regulation and endometriosis, its precise genetic etiology remains elusive. Methyltransferase-like 14 (METTL14), a crucial component of the N6-methyladenosine (mA) RNA methyltransferase complex and an RNA binding scaffold, is known to play a pivotal role in various human diseases.
View Article and Find Full Text PDFStress-relieving plant growth-promoting bacterial co-inoculation enhances nodulation and nitrogen uptake in black gram under nitrogen-free saline conditions.
Front Microbiol
January 2025
National Bureau of Agriculturally Important Microorganism, Mau, India.
Non-halophytic plants are highly susceptible to salt stress, but numerous studies have shown that halo-tolerant microorganisms can alleviate this stress by producing phytohormones and enhancing nutrient availability. This study aimed to identify and evaluate native microbial communities from salt-affected regions to boost black gram () resilience against salinity, while improving plant growth, nitrogen uptake, and nodulation in saline environments. Six soil samples were collected from a salt-affected region in eastern Uttar Pradesh, revealing high electrical conductivity (EC) and pH, along with low nutrient availability.
View Article and Find Full Text PDFBiofilm morphology and antibiotic susceptibility of methicillin-resistant (MRSA) on poly-D,L-lactide--poly(ethylene glycol) (PDLLA-PEG) coated titanium.
Biofilm
December 2024
Department of Biomaterials, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Biodegradable polymeric coatings are being explored as a preventive strategy for orthopaedic device-related infection. In this study, titanium surfaces (Ti) were coated with poly-D,L-lactide (PDLLA, (P)), polyethylene-glycol poly-D,L-lactide PEGylated-PDLLA, (PP20)), or multi-layered PEGylated-PDLLA (M), with or without 1 % silver sulfadiazine. The aim was to evaluate their cytocompatibility, resistance to biofilm formation, and their potential to enhance the susceptibility of any biofilm formed to antibiotics.
View Article and Find Full Text PDFMarital status and risk of type 2 diabetes among middle-aged and elderly population: a systematic review and meta-analysis.
Front Med (Lausanne)
January 2025
Student Research Committee, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Background: Marital status is among the factors influencing type 2 diabetes mellitus (T2DM). However, the precise relationship remains incompletely understood. This meta-analysis aims to evaluate the association between marital status and the incidence of T2DM.
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