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Vaccination of pregnant women: an overview of European policies and strategies to promote it.
Front Public Health
December 2024
Department of Medicine and Surgery, University of Perugia, Perugia, Italy.
Maternal immunization is a valuable tool for protecting mother and unborn child from vaccine-preventable diseases. However, the implementation of strategies for vaccinating pregnant women has only recently gained traction. This work is aimed at providing an overview of European vaccination strategies and gathering evidence on interventions enhancing vaccination knowledge, attitudes, and behaviors (KAB) in pregnant women.
View Article and Find Full Text PDFAnalytical Challenges in Novel Pentavalent Meningococcal Conjugate Vaccine (A, C, Y, W, X).
Vaccines (Basel)
October 2024
Serum Institute of India Pvt Ltd., Pune 411 028, India.
Multivalent meningococcal conjugate vaccines are a significant focus for the scientific community in light of the WHO's mission to defeat meningitidis by 2030. Well-known meningococcal vaccines such as MenAfriVac, Nimenrix, Menveo, and MenQuadfi are licensed in various parts of the world and have been successful. Recently, the World Health Organization (WHO) qualified MenFive (meningococcal A, C, Y, W, and X) conjugate vaccine, further enhancing the battery of vaccines against meningitis.
View Article and Find Full Text PDFInfluence of Hematocrit and Storage Temperature on the Stability of Dried Blood Samples in Serological Analyses of Tetanus, Diphtheria, and Pertussis.
Diagnostics (Basel)
October 2024
Microbiology Department, Clínica Universidad de Navarra, 31008 Pamplona, Spain.
Article Synopsis
- Dried blood spots (DBSs) allow researchers to study antibodies for diseases like diphtheria, tetanus, and pertussis without needing blood from veins, making sample collection easier.
- In a study with 64 blood samples, the effectiveness of DBSs in tracking these diseases was assessed, showing high sensitivity and specificity for diphtheria and tetanus, while no protection against pertussis was found.
- The correlation between antibody levels in DBSs and plasma was strong for diphtheria and tetanus even after 4 months of storage at low temperatures, but significantly weaker for pertussis, indicating that DBSs are reliable for some markers but not all.
Pertussis Notification Rate and Tdpa Vaccine/Booster Coverage in Adults: An Opportunity for an Epidemiological Observatory in Primary Care.
Infect Dis Rep
September 2024
Italian College of General Practitioners and Primary Care, 50142 Florence, Italy.
: In recent years, Europe has experienced a significant increase in pertussis cases. One reason behind this rise is the decline in diphtheria-tetanus-pertussis (dTap) booster coverage among adults. Currently, Italy lacks a reliable monitoring system to track pertussis infections and vaccine coverage among adults.
View Article and Find Full Text PDFRe-inventing traditional aluminum-based adjuvants: Insight into a century of advancements.
Int Rev Immunol
September 2024
Amity Institute of Microbial Technology, Amity University Rajasthan, Jaipur, India.
Aluminum salt-based adjuvants like alum, alhydrogel and Adju-Phos are by far the most favored clinically approved vaccine adjuvants. They have demonstrated excellent safety profile and currently used in vaccines against diphtheria, tetanus, pertussis, hepatitis B, anthrax etc. These vaccinations cause minimal side effects like local inflammation at the injection site.
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