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Incidence and risk factors for acute kidney injury in children with nephrotic syndrome: a meta-analysis.
Front Pediatr
December 2024
Department of Pediatrics, The First Hospital of Quanzhou Affiliated to Fujian Medical University, Quanzhou, Fujian, China.
Article Synopsis
- Nephrotic syndrome (NS) is a common kidney condition in children that can lead to severe complications like acute kidney injury (AKI), prompting the need for early identification of high-risk patients.
- A comprehensive analysis of 11 studies showed that AKI occurs in about 29% of children with NS, with several significant risk factors like age of onset, gender, serum albumin levels, steroid response, and existing conditions such as infections and hypertension.
- The study utilized traditional and network meta-analyses to evaluate these risk factors, emphasizing the importance of recognizing these associations to improve management and outcomes for children with NS.
Intraluminal Insertion of 9-0 Nylon for Postoperative Choroidal Detachment After Preserflo MicroShunt Implantation: A Case Report.
Cureus
November 2024
Department of Ophthalmology and Visual Science, Chiba University Graduate School of Medicine, Chiba, JPN.
Preserflo MicroShunt (PMS) implantation is a minimally invasive surgical procedure for treating glaucoma. Postoperative hypotony, a common complication of PMS implantation, can be prevented and treated with 10-0 nylon insertion. In this report, we present a case of postoperative hypotony following PMS implantation that was treated with intraluminal insertion of 9-0 nylon.
View Article and Find Full Text PDFIPNA clinical practice recommendations on care of pediatric patients with pre-existing kidney disease during seasonal outbreak of COVID-19.
Pediatr Nephrol
December 2024
Pediatric Nephrology, Dialysis and Transplant Unit, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy.
The coronavirus disease 2019 (COVID-19) pandemic, instigated by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has profoundly impacted healthcare infrastructures around the globe. While children are usually asymptomatic or have mild symptoms, children with pre-existing kidney conditions require specialized attention. This pivotal report, championed by the International Pediatric Nephrology Association (IPNA), delivers precise and actionable recommendations tailored for pediatric patients with kidney ailments in this pandemic landscape.
View Article and Find Full Text PDFTrifunctional protein deficiency (TFP) is a disorder of fatty acid beta-oxidation associated with metabolic, cardiac, and liver dysfunction in severe forms. We present two siblings diagnosed by newborn screening and confirmed by biochemical testing at birth. Their clinical course was complicated by recurrent rhabdomyolysis, retinopathy, and hypoparathyroidism.
View Article and Find Full Text PDFExploration of the pathogenesis of nephrotic syndrome and traditional Chinese medicine intervention based on gut microbiota.
Front Immunol
December 2024
Department of Nephrology, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin, China.
Nephrotic syndrome (NS) represents a prevalent syndrome among various chronic kidney disease pathologies and is known for its higher severity and worse prognosis compared with chronic glomerulonephritis. Understanding its pathogenesis and identifying more effective treatment modalities have long been a concern of kidney specialists. With the introduction of the gut-kidney axis concept and the progress in omics technologies, alterations in the gut microbiota have been observed in primary and secondary NS.
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