An Arthrobacter beta-galactosidase has homology with the lysosomal acid beta-galactosidases from humans and mice and with a Xanthomonas manihotis enzyme. Phylogenetic analysis of the deduced amino acid sequence showed an unusual pattern, with this procaryotic enzyme clustering within the animal clade. The gene encodes a subunit of 52 kDa, and the enzyme appears to be active as a dimer. The enzyme hydrolyzed substrates with either a beta-1,4 or a beta-1,3 linkage.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC179077 | PMC |
| http://dx.doi.org/10.1128/jb.179.9.3064-3067.1997 | DOI Listing |
Publication Analysis
Top Keywords
arthrobacter beta-galactosidase
8
beta-galactosidase homology
8
novel arthrobacter
4
homology eucaryotic
4
eucaryotic beta-galactosidases
4
beta-galactosidases arthrobacter
4
homology lysosomal
4
lysosomal acid
4
acid beta-galactosidases
4
beta-galactosidases humans
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!