As many as 29 oncological patients with severe depression of hemopoiesis secondary to cytostatic therapy underwent transfusion of fetal liver cells (FLC) from human embryos in the 8-12 weeks stage of their development cryopreserved in 5% DMCO at -196 degrees C as to the method elaborated at the Institute of Problems in Cryobiology and Cryomedicine. A strong correlation was found between infusion of a certain FLC dose and rise in leucocyte counts, which rise occurred by day 13-16 (r = +0.846). A minimum FLC dose for the expected leucocyte count rise to be of the magnitude of 3.32.10(9)/1 appeared to be 10(9) cells. Transplantation had a beneficial effect on the immune status of the patients. There was not a single case of graft-versus-host reaction. The above method has been recommended for use in clinical settings.

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