One-hundred and fifty-five patients suffering from T. Capitis, T. Corporis, T. Cruris and T. Verisicolor participated in studies of topically applied griseofulvin. Various concentrations of the drug were prepared in an ointment form in a new solvent system. Successful results were obtained with the 2% preparation in cases of T. Corporis, T. Cruris and T. Versicolor. Failure of the therapy was observed in cases of T. Capitis. No side-effects occurred in any patient using the 2% preparation. In the opinion of the authors, topically applied griseofulvin in the new solvent system is safe and highly effective in the treatment of superficial dermatomycoses.
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http://dx.doi.org/10.1177/030006057700500517 | DOI Listing |
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