Early protection of puppies against canine parvovirus: a comparison of two vaccines.

J Am Anim Hosp Assoc

Department of Veterinary Medicine, University of Missouri, Columbia 65211, USA.

Published: July 1997

AI Article Synopsis

  • The study compared two commercially available vaccines for parvovirus in puppies and assessed their effectiveness by measuring antibody levels.
  • Puppies that received one specific vaccine showed significantly higher protective antibody titers shortly after vaccination and at various ages compared to the other vaccine.
  • Results indicated that this superior vaccine resulted in stronger and more timely immune responses, suggesting better protection against parvovirus in young dogs.

Article Abstract

Client-owned puppies randomly were assigned to receive one of two commercially available polyvalent vaccines. The response to the parvovirus portion of each vaccine was evaluated by determining antibody titers by hemagglutination inhibition. Significant differences were found between titers produced by the vaccines. Puppies vaccinated with one of the products had a more desirable result as demonstrated by a protective antibody titer after the first vaccination (p of 0.005), a protective antibody titer at a younger age (p of 0.02), a protective antibody titer by 12 weeks of age (p of 0.001), and a protective antibody titer by 16 weeks of age (p of 0.05). Puppies vaccinated with this product also had significantly higher titers at each sampling after vaccination.

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Source
http://dx.doi.org/10.5326/15473317-33-3-244DOI Listing

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