Objective: A cerebral function lateralization has been described in bulimic patients in positron emission tomography (PET) studies realized during a specific cognitive task. The purpose of this study was to evaluate, at rest, brain glucose metabolism in patients with bulimia nervosa.
Method: PET with (18-F)-fluorodeoxyglucose was used to evaluate cerebral glucose metabolism in 11 normal-weight bulimic girls compared to 11 age- and sex-matched healthy volunteers. Patients were diagnosed following DSM-IV and were off psychoactive medication.
Results: In comparison with control subjects, bulimic patients showed global and regional absolute hypometabolism of glucose. In relative values, only parietal cortex metabolism was significantly lower in bulimic patients. No correlation was found within groups for absolute or relative cerebral glucose metabolic rates (rCMRglu) and body mass index (BMI), anxiety scores, or Hamilton scores of depression.
Discussion: Since previous studies have demonstrated similar disturbances in anorectic patients, we hypothesized that these observations could be a consequence of neurobiological perturbations following nutritional deficiencies or a particular cerebral dysfunction in eating disorders.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1002/(sici)1098-108x(1997)21:4<313::aid-eat2>3.0.co;2-r | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Acute abdominal aortic occlusion due to gastric dilatation caused by pyloric stenosis in a 62-year-old patient.
J Vasc Surg Cases Innov Tech
December 2024
Department of Vascular Surgery, National Medical Institute of the Ministry of the Interior and Administration, Warsaw, Poland.
Acute gastric dilatation leading to compromised vascular visceral vascular flow is an exceptionally rare complication typically described in patients with bulimia or anorexia following binge episodes. We present a fatal case involving a non-bulimic patient who experienced an acute gastric dilatation secondary to pyloric stenosis. Despite intensive treatment, the patient succumbed to complications arising from acute reperfusion syndrome.
View Article and Find Full Text PDFDissecting implicit food-related behaviors in Binge Eating Disorder and obesity: insights from a mobile approach-avoidance framework.
Front Psychol
October 2024
Department of Neuroscience, University of Padua, Padova, Italy.
Introduction: Bulimic episodes experienced by patients with Binge Eating Disorder (BED) might be sustained by an enhanced behavioral propensity to approach food stimuli.
Methods: To test this hypothesis, automatic approach avoidance tendencies toward high-calorie foods (HCF), low-calorie foods (LCF), and neutral objects were assessed in a group of 23 patients with BED, and their performance was compared to the one of 17 patients with obesity without BED and a group of 32 normal weight participants. All participants performed a mobile approach-avoidance task in which they were required to approach and avoid different stimuli by respectively pulling their phone toward themselves or pushing it away.
Prevalence and Correlates of Self-Reported ADHD Symptoms in Bariatric Patients: Focus on Mood and Anxiety Comorbidity, Disordered Eating, and Temperamental Traits.
Obes Surg
September 2024
Department of Clinical and Experimental Medicine, University of Pisa, Via Savi 10, 56126, Pisa, Italy.
Purpose: Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental condition characterized by inattention, hyperactivity, and impulsivity. A positive association between ADHD and obesity has been observed, especially in adult samples. In this study, prevalence and correlates of self-reported symptoms indicative of a positive screening for ADHD were examined in patients seeking bariatric treatment.
View Article and Find Full Text PDFWeb-Based Cognitive Behavioral Treatment for Bulimia Nervosa: A Randomized Clinical Trial.
JAMA Netw Open
July 2024
Department of Psychology, Heidelberg University, Germany.
Importance: Despite the existence of effective treatments, many individuals with bulimia nervosa (BN) do not receive evidence-based therapies. Integrating digital interventions into routine care might reach more patients and reduce the clinical burden of BN.
Objective: To evaluate the effectiveness of a web-based cognitive behavioral self-help intervention for individuals with BN.
Impulsivity and reward and punishment sensitivity among patients admitted to a specialized inpatient eating disorder treatment program.
Front Psychiatry
May 2024
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, United States.
Article Synopsis
- Eating disorders (EDs) are linked to impulsivity and sensitivity to rewards and punishments, which may influence their risk and treatment outcomes, but research is limited.
- A study involving 228 inpatient ED patients examined the relationship between impulsivity and ED symptoms, revealing that lower impulsivity is seen in anorexia nervosa (restricting type) compared to other ED types, with impulsivity correlating with bulimic symptoms at admission.
- The findings suggest that while impulsivity can differentiate between ED types, it does not predict treatment success or outcomes, highlighting the need for further research on personality traits in relation to EDs.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!