Changes of the mean firing rate of neurons in the posterior hypothalamus on a regional increase or decrease in the midbrain temperature (0.6-2.0 degrees C) and skin temperature (3-5 degrees C) were studied in unanesthetized rabbits. In the posterior hypothalamus, neurons were found which responded both to the midbrain and skin temperature changes. The data suggest that the posterior hypothalamus takes part in the integration of signals from different central and peripheral temperature sensitive agents.
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