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Current status of drug therapy for chronic hepatitis B.
World J Gastroenterol
January 2025
Division of Liver Surgery, Department of General Surgery and Laboratory of Liver Surgery, and State Key Laboratory of Biotherapy and Collaborative Innovation Center of Biotherapy, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China.
In this editorial, we comment on the article by Meng . Chronic hepatitis B (CHB) is a significant global health problem, particularly in developing countries. Hepatitis B virus (HBV) infection is one of the most important risk factors for cirrhosis and hepatocellular carcinoma.
View Article and Find Full Text PDF[Controlling cystic echinococcosis: outlook in the 21st centuryControle da equinococose/hidatidose cística: perspectivas no século XXI].
Rev Panam Salud Publica
January 2025
Centro Panamericano de Fiebre Aftosa Unidad de Salud Pública Veterinaria Organización Panamericana de la Salud Río de Janeiro Brasil Centro Panamericano de Fiebre Aftosa, Unidad de Salud Pública Veterinaria, Organización Panamericana de la Salud, Río de Janeiro, Brasil.
Cystic echinococcosis (CE) is a serious public health problem in South America, one that the Pan American Health Organization (PAHO) has included in its Plan of Action for the Control of Neglected Infectious Diseases. A logical framework for CE control was defined: this includes establishing the objective to be achieved (eradication or elimination as a public health problem) and determining levels of endemicity which serve as a guide for establishing frequencies of intervention (high endemicity, endemic, and low endemicity, according to rates in the different hosts). There are two validated tools for CE control: systematic deworming of dogs using praziquantel (PZQ) and systematic vaccination of sheep with recombinant EG95 protein, or a combination of both tools.
View Article and Find Full Text PDFPsychogenic hearing loss in children and adolescents. Diagnosis and psychotherapy.
Ann Med
December 2025
Department of Pediatric Otolaryngology, Centre of Postgraduate Medical Education, Warsaw, Poland.
Introduction: Psychogenic hearing loss is often neglected in the differential diagnosis of hearing disorders. In a difficult diagnostic process and treatment of psychogenic hearing loss disorder, the close cooperation of the audiologist, psychologist, patient, and his family is required. The study aimed to improve the knowledge and understanding of psychogenic hearing loss, establish a differential diagnosis in audiological tests in children, determine diagnostic procedures and finally apply adequate therapeutic procedures.
View Article and Find Full Text PDFMonkeypox: a re-emergent virus with global health implications - a comprehensive review.
Trop Dis Travel Med Vaccines
January 2025
Department of Botany and Microbiology, Faculty of Science, Damanhour University, Damanhour, Egypt.
Monkeypox virus (MPXV) is an enclosed, double-stranded DNA virus from the Orthopoxvirus genus, which also contains variola, vaccinia, and cowpox. MPXV, which was once confined to West and Central Africa, has recently had a rebound, spreading beyond its original range since 2017. The virus is distinguished by its unique morphology, which includes an oval or brick-shaped structure and a complex lipid and protein makeup.
View Article and Find Full Text PDFNovel and recurrent genetic variants associated with male and female infertility.
J Appl Genet
January 2025
Department of Medical Genetics, Institute of Mother and Child, Warsaw, Poland.
Recently, the knowledge of the genetic basis of fertility disorders has expanded enormously, mainly thanks to the use of next-generation sequencing (NGS). However, the genetic cause of infertility, in the majority of patients, is still undefined. The aim was to identify novel and recurrent pathogenic/likely pathogenic variants in patients with isolated infertility or puberty delay using a targeted NGS technique.
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