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Little is known about the impact of environmental pollution on thyroid function in the non-occupationally exposed population of Kazakhstan. This study aimed to investigate serum levels of thyroxine (T4), thyroid-stimulating hormone (TSH), and anti-thyroid peroxidase (TPO) antibodies in the environmentally exposed population of Kazakhstan in relation to symptoms of anxiety. A total of 1,388 nominally healthy individuals residing in areas exposed to three major types of environmental pollution prevalent in Kazakhstan-non-ferrous metallurgy, condensate gas extraction, and activities of the Semipalatinsk Nuclear Test Site (SNTS)-were enrolled.
View Article and Find Full Text PDFUse of Machine Learning to Predict the Incidence of Type 2 Diabetes Among Relatively Healthy Adults: A 10-Year Longitudinal Study in Taiwan.
Diagnostics (Basel)
December 2024
Department of Family Medicine, Taichung Veterans General Hospital, Taichung 407219, Taiwan.
: The prevalence of diabetes is increasing worldwide, particularly in the Pacific Ocean island nations. Although machine learning (ML) models and data mining approaches have been applied to diabetes research, there was no study utilizing ML models to predict diabetes incidence in Taiwan. We aimed to predict the onset of diabetes in order to raise health awareness, thereby promoting any necessary lifestyle modifications and help mitigate disease burden.
View Article and Find Full Text PDFEvaluation of a point-of-care test for quantitative determination of total thyroxine in feline serum.
J Feline Med Surg
January 2025
Department of Veterinary Medicine and Animal Sciences (DIVAS), University of Milan, Lodi (LO), Italy.
Objectives: Total thyroxine (TT4) evaluation is the most commonly used first-line test for the diagnosis and monitoring of cats with hyperthyroidism. Vcheck T4 is a point-of-care immunoassay that measures TT4 using a Vcheck V200 analyser. This study aimed to evaluate the analytic performance of the Vcheck T4 assay in feline sera and the agreement in the classification of normal, high and low TT4 concentrations of Vcheck T4 with those measured by an enzyme immunoassay (EIA).
View Article and Find Full Text PDFDeveloping Benchmarking Metrics for Appropriate Ordering of Vitamin D, Thyroid Testing, and Iron Workups.
J Appl Lab Med
January 2025
Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, United States.
Background: Laboratory stewardship programs are increasingly adopted to enhance test utilization and improve patient care. Despite their potential, implementation within complex healthcare systems remains challenging. Benchmarking metrics helps institutions compare their performance against peers or best practices.
View Article and Find Full Text PDFGender differences of neurometabolic and neuroendocrine alternations and its lateralization in adolescents with major depressive disorder.
BMC Psychiatry
December 2024
Department of Psychiatry, First Affiliated Hospital, Jinan University, Guangzhou, 510630, China.
Background: The clinical characteristics of major depressive disorder (MDD) in adolescents show notable gender-related differences, but the cause of these differences is still not understood. The current research concentrates on the changes in neurometabolism and neuroendocrine function, aiming to identify differences in endocrine function and brain metabolism between male and female adolescents with MDD.
Methods: A total of 121 teenagers diagnosed with MDD (43 males and 78 females) were enlisted as participants.
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