Background: Female back pain is a clinical problem-especially low back pain with symptoms from the pelvic posterior region-that is often aggravated in connection with pregnancy and childbirth. Hormones have been suggested as an aetiologic factor. This study is aimed to determine whether additional hormone preparations, i.e. oral contraceptives (OC), may contribute to the increased frequency of such pain.
Methods: A register study was conducted to investigate the use of drugs and health care use in a female population with known OC consumption. Specifically, we registered the number of primary health care visits for low back pain, comparing OC users with non-OC using age-matched women with otherwise equal circumstances.
Results: OC users recorded a significantly higher incidence of low back symptoms during the study period compared to non-users. Pregnancy was not found to be a confounding factor.
Conclusions: The intriguing association between OC use and a higher incidence of low back pain, does not enable us to conclude that there is a causal connection, but it should lead to further studies.
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http://dx.doi.org/10.1093/ije/26.1.71 | DOI Listing |
Adv Healthc Mater
March 2025
Department of Orthopaedics, Key Laboratory of Structural Malformations in Children of Zhejiang Province, Key Laboratory of Orthopaedics of Zhejiang Province, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325000, China.
Intervertebral disc degeneration (IVDD) is a major cause of low back pain, where oxidative stress and mitochondrial dysfunction are key contributors. Additionally, ferroptosis, an iron-dependent form of cell death, is identified as a critical mechanism in IVDD pathogenesis. Herein, the therapeutic potential of gallic acid (GA)-derived PGA-Cu nanoparticles, enhanced with functional octapeptide (Cys-Lys-His-Gly-d-Arg-d-Tyr-Lys-Phe, SS08) to build the mitochondria-targeted nanoparticles (PGA-Cu@SS08), and embedded within a hydrogel matrix to form a nanocomposite hydrogel, is explored.
View Article and Find Full Text PDFJ Pain Res
March 2025
Program of Physical Therapy, Department of Medical Rehabilitation Sciences, College of Applied Medical Sciences, King Khalid University, Abha, 61421, Saudi Arabia.
Background: Between half and three quarters of the working-age population in today's industrialized globe suffers from lower back pain. The presence of a myofascial trigger point-a hyperirritable painful area comprised of a small number of muscle fibers-identifies mechanical back pain sufferers as suffering from myofascial pain syndrome, a chronic pain disorder. This research objectives to determine whether mechanical back pain patients' pain severity and functional disabilities are influenced by electromagnetic field therapy.
View Article and Find Full Text PDFJ Pain Res
March 2025
Affiliated Hospital of Gansu University of Chinese Medicine, Lanzhou, Gansu, 730000, People's Republic of China.
Orthop J Sports Med
March 2025
Department of Orthopaedic Surgery, UPMC Freddie Fu Sports Medicine Center, Pittsburgh, Pennsylvania, USA.
Background: Full-thickness, transtendinous supraspinatus rotator cuff tears involve a significant portion of the remanent tendon attached to the footprint.
Purpose: To compare outcomes and failure rates for arthroscopic side-to-side (STS) suture repair for transtendinous tears versus traditional double-row repair for common tendon-to-bone type tears.
Study Design: Cohort study; Level of evidence, 3.
Pain Rep
April 2025
Division of Biokinesiology and Physical Therapy, University of Southern California, Los Angeles, CA, USA.
Introduction: Effective prevention and management strategies for chronic pain remain elusive. This has prompted investigations into biomarkers to better understand the mechanisms underlying pain development and persistence. One promising marker is low peak alpha frequency (PAF), an electroencephalography (EEG) measure that has been associated with increased sensitivity during acute experimental pain.
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