A large sample of non-clinical subjects were screened and those who reported experiencing relatively frequent intrusive thoughts with associated neutralizing were selected. These subjects were randomly allocated to one of two conditions: both groups listened to repeated recorded presentations of one of their intrusive thoughts and were then required either to (a) neutralize it, or (b) distract themselves for a similar period. Ratings of discomfort were taken during this procedure (first phase), and during identical presentations of the same thought without neutralizing or distracting (second phase). Results showed that the group who neutralized during the first phase experienced significantly more discomfort during the second phase and significantly stronger urges to neutralize and distract. There was also evidence that engaging in neutralizing responses during the first phase made it difficult to stop neutralizing during the second phase. The results are considered in the context of the cognitive-behavioural hypothesis that obsessional disorders develop as a consequence of neutralizing normal intrusive thoughts.
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http://dx.doi.org/10.1016/s0005-7967(96)00112-x | DOI Listing |
J Psychiatr Res
December 2024
Department of Psychiatry, The First Affiliated Hospital of China Medical University, Shenyang, 110001, China. Electronic address:
Obsessive-compulsive disorder (OCD) is a chronic and disabling psychiatric disorder characterized by recurrent intrusive thoughts or repetitive behaviors. We sought to better understand the structure of gut microbiota in first visit registration, treatment-naive children and adolescents with OCD, and the relationship between gut microbiota and fecal metabolites. Thus we studied the gut microbial population using 16 S rRNA sequencing in 49 children (8-17 years of age) with OCD, 42 healthy controls (HCs).
View Article and Find Full Text PDFProc Natl Acad Sci U S A
January 2025
Department of Psychology, University of York, York YO10 5DD, United Kingdom.
Sleep disturbances are associated with intrusive memories, but the neurocognitive mechanisms underpinning this relationship are poorly understood. Here, we show that sleep deprivation disrupts prefrontal inhibition of memory retrieval, and that the overnight restoration of this inhibitory mechanism is associated with time spent in rapid eye movement (REM) sleep. The functional impairments arising from sleep deprivation are linked to a behavioral deficit in the ability to downregulate unwanted memories, and coincide with a deterioration of deliberate patterns of self-generated thought.
View Article and Find Full Text PDFBiol Psychiatry Cogn Neurosci Neuroimaging
December 2024
Department of Psychiatry and Behavioral Medicine, Medical College of Wisconsin, Milwaukee, WI, USA. Electronic address:
Background: Prolonged Grief Disorder is a multidimensional condition with adverse health consequences. We hypothesized that enhanced negative emotional bias characterizes this disorder and underlies its key clinical symptoms.
Methods: In a cross-sectional design, chronically grieving older adults (61.
Front Psychol
December 2024
War Related Illness and Injury Study Center, VA Palo Alto Health Care System, Palo Alto, CA, United States.
J Eat Disord
December 2024
Department of Social and Developmental Psychology, University of Rome Sapienza, via dei Marsi 78, Rome, 00185, Italy.
Background: The long-lasting consequences of the COVID-19 pandemic on the psychological well-being of young people have become an emerging research topic, which still raises several questions for post-pandemic interventions at the individual and community levels. This research investigated the relationship between COVID-19 pandemic life events and the occurrence of binge eating behaviors in emerging adults, hypothesizing indirect effects of the emotional impact of pandemic events and social anxiety.
Methods: Data collection was conducted in November and December 2021 in Italy, involving 286 university students aged 18 to 30 years (M = 20.
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