Folate intake in young women and their knowledge of preconceptional folate supplementation to prevent neural tube defects.

Eur J Obstet Gynecol Reprod Biol

Centre for Reproduction, Growth and Development, School of Medicine, University of Leeds, UK.

Published: December 1996

Objectives: To ascertain knowledge of periconceptional folate for prevention of neural tube defect (NTD) and to estimate folate intake in young women.

Study Design: Three hundred young women were questioned about their knowledge of folate for prevention of NTD. Their folate intake was assessed by food frequency questionnaire.

Results: Fourteen per cent of 16-19 year olds and 41% of undergraduates were aware of the need to increase folate intake before conception. Median folate intake was estimated to be 235 micrograms/d in 16-19 year olds and 248.5 micrograms/d in undergraduates. More than a quarter of women in both groups had folate intakes less than the reference nutrient intake (RNI) (200 micrograms/d) below which prevalence of NTD rises dramatically and these women would therefore be at increased risk of having a child with NTD should they have an unplanned pregnancy.

Conclusions: Strategies are required to increase folate intake among young women and inform them of the benefit of peri-conceptional folate supplementation.

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http://dx.doi.org/10.1016/s0301-2115(95)02584-7DOI Listing

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