Chlamydia trachomatis is responsible for urogenital infections, often minimally symptomatic, revealed by their complications. Mycoplasmas, mainly Ureaplasma urealyticum and Mycoplasma hominis, are normal commensal organisms of the genital tract, which sometimes makes it difficult to determine their pathogenicity. However, they are responsible for urogenital infections, and U. urealyticum is a pathogen in male urethris. The laboratory diagnosis is based on specific techniques adapted to these microorganisms. In the case of C. trachomatis, it has benefited from the recent progress in molecular biology techniques. The therapeutic approach is common to both types of organisms: tetracyclines and macrolides are the major antibiotics used in the treatment of these urogenital infections.
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