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Isolation of from bronchoalveolar lavage of an immunocompetent host presenting with cavitating pneumonia: Contaminant or Causative?
Germs
September 2023
MD, Department of Respiratory Medicine, St Luke's Hospital, Kilkenny, Ireland.
Introduction: is a Gram-negative, facultative anaerobic bacillus that is most often found as an enteric commensal. It is seldom considered to be pathogenic in immunocompetent individuals.
Case Report: We describe a case of a 23-year-old, previously healthy male, who presented to the emergency department with a two-day history of hemoptysis, mild dyspnea, pleuritic chest pain, fevers, and chills.
The Gram-Negative Bacilli Isolated from Caves- and and a Review of Their Involvement in Human Infections.
Int J Environ Res Public Health
February 2022
Emil Racovita Institute of Speleology, Cluj-Napoca Department, Clinicilor 5, 400006 Cluj-Napoca, Romania.
Article Synopsis
- * A total of 447 human infection cases related to these bacteria were reviewed, with 58.61% being infections and 41.39% being infections.
- * Most infections occur in patients with underlying health issues; however, 17.9% were in previously healthy individuals, and the study notes a total of 10 deaths related to these infections.
pneumonia: from bees to human beings.
Germs
June 2021
MD, MSc, Fundación Neumológica Colombiana - Universidad de La Sabana, Fundación Cardioinfantil, Calle 163A # 13B - 85 Bogotá, Colombia.
Introduction: is an enterobacteria that is a common inhabitant of the gastrointestinal flora of bees, birds, fish, and mammals. In humans this enterobacteria has been recovered from the oropharynx and the gastrointestinal tract but it has been rarely reported as a pathogen and usually identified as hospital-acquired enterobacteria.
Case Report: We describe a case of a 57-year-old woman, previously healthy, with a 7-day history of cough with brown sputum, sudden onset of chills, subjective fever, malaise, and pleuritic pain in the right hemithorax.
Comparative genomic analysis of the Hafnia genus reveals an explicit evolutionary relationship between the species alvei and paralvei and provides insights into pathogenicity.
BMC Genomics
October 2019
Key Laboratory of Molecular Microbiology and Technology of the Ministry of Education, TEDA College, Nankai University, Tianjin, People's Republic of China.
Article Synopsis
- The Hafnia genus is an opportunistic pathogen associated with various infections, but its taxonomy and role in human disease are not well understood.
- Researchers conducted a comparative genomic analysis to clarify the taxonomy of Hafnia, uncover species-specific genes linked to ecological and pathogenic traits, and examine virulence-related genetic profiles.
- The study revealed two distinct Hafnia species, alvei and paralvei, identified specific genetic characteristics associated with their pathogenic potential, and recognized various resistance genes, highlighting the complexity of their virulence mechanisms.
Clinical characteristics of nosocomial and community-acquired extraintestinal infections caused by Hafnia alvei.
Scand J Infect Dis
January 2006
Servicio de Medicina Interna I, Hospital Universitario Central de Asturias, Oviedo, Spain.
36 episodes (25 nosocomial and 11 community-acquired) of infections caused by Hafnia alvei showed that this bacterium is responsible for serious infections in adults, specially in hospitalized patients with underlying chronic diseases, subjected to invasive procedures or even under antibiotic treatment.
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