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The Displaced Fleck Sign: Description of a Radiographic Finding Consistent with Grade III Thumb Ulnar Collateral Ligament Tears with Stener Lesions.
J Hand Surg Am
January 2025
Department of Orthopaedic Surgery, University of Utah Hospital, Salt Lake City, UT. Electronic address:
Purpose: Controversy exists regarding the optimal imaging modality (magnetic resonance imaging, ultrasound, stress radiographs) for identification of patients with grossly unstable thumb metacarpophalangeal (MCP) ulnar collateral ligament (UCL) injuries or Stener lesions. We characterize a radiographic sign for this purpose. The "displaced fleck sign" is a small avulsion fracture from the ulnar proximal phalanx base that is displaced proximal to the MCP joint line.
View Article and Find Full Text PDFMechanism Study of E2F8 Activation of SPC25-Mediated Glutamine Metabolism Promoting Immune Escape in Lung Adenocarcinoma.
Immunology
January 2025
Department of Respiratory and Critical Care Medicine, Longyan First Affiliated Hospital of Fujian Medical University, Longyan, China.
Tumour cell immune infiltration is linked to spindle pole component 25 (SPC25). The purpose of this work was to examine the function and molecular mechanism of SPC25 in immune escape in lung adenocarcinoma (LUAD). SPC25 expression in LUAD was examined using The Cancer Genome Atlas (TCGA) database, and RT-qPCR was used to confirm the results.
View Article and Find Full Text PDFWhich screw corridors can be used for bilateral fragility fractures of the pelvis with a transverse fracture component (FFP IVb)?
Injury
January 2025
Clinic and Polyclinic for Orthopaedics, Trauma Surgery and Plastic Surgery, University of Leipzig Medical Center, Leipzig, Germany.
Background: Fragility fractures of the pelvis are becoming increasingly important in an ageing society. However, they are under-represented in the current research literature. In particular, unstable bilateral fragility fractures of the sacrum (FFP IVb) benefit from surgical treatment, but individual fracture patterns need to be considered in the surgical decision.
View Article and Find Full Text PDFDevelopment of a machine learning algorithm to identify cauda equina compression on MRI scans.
World Neurosurg
January 2025
Department of Neurosurgery, Manchester Centre for Clinical Neurosciences, Salford Royal Hospital, M6 8HD, Manchester, England, United Kingdom.
Objective: Cauda Equina Syndrome (CES) poses significant neurological risks if untreated. Diagnosis relies on clinical and radiological features. As the symptoms are often non specific and common, the diagnosis is usually made after a MRI scan.
View Article and Find Full Text PDFEarly Identification of Poorly Performing Implants in Michigan With the Example of the Vanguard XP.
Arthroplast Today
December 2024
The CORE Institute, Phoenix, AZ, USA.
Background: Arthroplasty registries play a critical role in improving the quality of care and performing post-market surveillance of medical devices. We report the Michigan Arthroplasty Registry Collaborative Quality Initiative (MARCQI) findings specific to the Biomet Vanguard XP bicruciate-retaining total knee implant.
Methods: Data were collected from MARCQI's 2019 report (February 15, 2012, through December 31, 2018).
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