AI Article Synopsis
- The study examined the trachea and bronchi of neonatal pigs after they were infected with Mycoplasma hyopneumoniae to observe changes over time using advanced microscopy techniques.
- Severe bronchial lesions were found in all infected pigs, particularly in the more affected lung areas.
- As time progressed post-inoculation, the amount of mycoplasmas and immune cells increased while the number of cilia on the epithelial cells decreased.
Article Abstract
Areas of trachea and right apical and right dorsal diaphragmatic bronchi from gnotobiotic neonatal pigs were examined by scanning electron and transmission electron microscopy at 7, 13, and 21 days after pigs were given intranasal inoculation of Mycoplasma hyopneumoniae. Similar areas were examined by scanning electron microscopy from 2 noninoculated neonatal pigs. Tracheal and bronchial lesions were observed in all inoculated pigs. Severe bronchial lesions were in grossly affected lobes. Early infection consisted of mycoplasmas on ciliated epithelial cells. As the interval between inoculation and euthanasia increased, mycoplasmas and leukocytes on the tracheal and bronchial surfaces became more numerous and fewer cilia remained.
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