AI Article Synopsis
- Eye movements were analyzed in two patients with pontine brain lesions, using imaging techniques for diagnosis.
- Impairments in eye movements were linked to specific areas of damage: unilateral lesions affected saccades, while other lesions impacted smooth pursuit.
- The study reinforced the role of pontine nuclei as crucial for coordinating both horizontal and vertical eye movements, especially after observing the effects of bilateral lesions.
Article Abstract
Eye movements were studied in two patients with pontine lesions identified by magnetic resonance imaging in one patient and computerized tomography, with neuropathological correlation in another patient. Impairment of ipsilateral saccades were explained by unilateral lesion of the paramedian pontine reticular formation. Ipsilateral dorsolateral and lateral pontine nuclei lesions results in unilateral impairment of smooth pursuit. Bilateral damage to the dorsomedian pontine nuclei result in bidirectional horizontal smooth pursuit deficit, predominantly towards the more pathologic affected side. In addition, these bilateral lesions may also account for impairment of vertical smooth pursuit. These findings confirm that pontine nuclei are an important relay for horizontal and vertical smooth pursuit movements.
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