Effect of recording site on postpacing interval measurement during catheter mapping and entrainment of postinfarction ventricular tachycardia.

Introduction: During entrainment of reentrant ventricular tachycardia (VT), the difference between the postpacing interval (PPI) and the VT cycle length (VTCL) measured at the pacing site is an indication of the conduction time from the pacing site to the reentry circuit. The difference is usually < or = 30 msec at successful ablation sites. However, electrical noise during pacing sometimes obscures the electrograms recorded directly from the pacing site. The objective of this study is to determine if the PPI-VTCL difference measured at the mapping catheter electrodes proximal to the stimulating electrode accurately predicts the PPI-VTCL difference at the stimulating electrode.

Methods And Results: Endocardial catheter mapping was performed in 26 patients with infarct-related VT. At 191 sites during 56 VTs, unipolar pacing from the distal electrode entrained VT and electrograms recorded from the mapping catheter were discernable following pacing in both the bipolar recordings from the distal electrode pair (BI 1-2) and the electrode pair 6 mm proximal to the distal electrode (BI 3-4). The PPI-VTCL difference at BI 1-2 correlated well with that measured at BI 3-4 (r = 0.88, P = 0.001). A PPI-VTCL difference at BI 3-4 < or = 30 msec predicted a PPI-VTCL difference at BI 1-2 < or = 30 msec with a sensitivity of 95%, specificity of 87 %, and predictive accuracy of 91%.

Conclusions: Measurement of the PPI from electrodes proximal to the stimulating electrode is a reasonable alternative when the PPI cannot be assessed from the pacing electrode.