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Real-Time Monitoring of Electrode Surface Changes in Fast-Scan Cyclic Voltammetry Using Fourier Transform Electrochemical Impedance Spectroscopy.
ACS Omega
January 2025
Department of Biomedical Engineering, Hanyang University, Seoul 04763, Republic of Korea.
Fast-scan cyclic voltammetry (FSCV) is a widely used electrochemical technique to measure the phasic response of neurotransmitters in the brain. It has the advantage of reducing tissue damage to the brain due to the use of carbon fiber microelectrodes as well as having a high temporal resolution (10 Hz) sufficient to monitor neurotransmitter release in vivo. During the FSCV experiment, the surface of the carbon fiber microelectrode is inevitably changed by the fouling effect.
View Article and Find Full Text PDFExploring physiological responses through electrodermal activity (EDA) for evaluating the impact of universal design features in a hotel environment.
Disabil Rehabil Assist Technol
January 2025
Industrial and Systems Engineering, University at Buffalo, Buffalo, NY, USA.
The aim of this study was to explore the feasibility of using electrodermal activity (EDA) to detect changes in physiological arousal linked to perceptions of accommodations, focusing on universal design (UD) features. In environments like hotels, designers must consider wellness, social integration, and cultural appropriateness to effectively implement UD. Challenges exist with implementing and evaluating UD to accommodate diverse user needs due to conflicting definitions and application issues.
View Article and Find Full Text PDFAge-Dependent Bi-Phasic Dynamics of Ly49CD8 Regulatory T Cell Population.
Aging Cell
December 2024
Department of Microbiology, Immunology and Molecular Genetics, Long School of Medicine, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
Aging is tightly associated with reduced immune protection but increased risk of autoimmunity and inflammatory conditions. Regulatory T cells are one of the key cells to maintaining immune homeostasis. The age-dependent changes in CD4Foxp3 regulatory T cells (Tregs) have been well documented.
View Article and Find Full Text PDFDoes intermittent nutrition enterally normalise hormonal and metabolic responses to feeding in critically ill adults? A protocol for the DINE-Normal proof-of-concept randomised parallel-group study.
BMJ Open
November 2024
Anaesthesia, Pain and Critical Care, School of Physiology, Pharmacology & Neuroscience, University of Bristol, Bristol, UK.
Introduction: Over half of patients who spend >48 hours in the intensive care unit (ICU) are fed via a nasogastric (NG) tube. Current guidance recommends continuous delivery of feed throughout the day and night. Emerging evidence from healthy human studies shows that NG feeding in an intermittent pattern (rather than continuous) promotes phasic hormonal, digestive and metabolic responses that are important for effective nutrition.
View Article and Find Full Text PDFCharacteristics of altered biventricular hemodynamics after arterial switch operation for patients with d-transposition of the great arteries with preserved ejection fraction: a four-dimensional (4D) flow cardiovascular magnetic resonance (CMR) study.
Quant Imaging Med Surg
October 2024
Department of Radiology, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Background: The long-term monitoring of biventricular function is essential to identify potential functional decline in patients following the arterial switch operation (ASO). The underlying pathophysiological mechanisms responsible for altered biventricular hemodynamics in ASO patients are not yet well understood. This study sought to: (I) compare the biventricular kinetic energy (KE) and vorticity of ASO patients and age- and sex-matched controls; (II) investigate the associations of four-dimensional (4D) flow biventricular hemodynamics parameters and neo-aortic root dilation, supravalvular pulmonary stenosis, and pulmonary artery transvalvular pressure difference.
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