In a period of 10 years we performed renal biopsies in 13 patients with systemic lupus erythematosis, the results showed mild changes and focal glomerulonephritis in 30%, diffuse glomerulonephritis in 23% and membranous nephropathy and sclerotic glomerulonephritis in 15% of patients. In the follow-up period three patients died. Prognosis of severe lupus nephritis is better nowadays because of improved therapy. Adverse effects of the applied therapy should not be overlooked while arterial hypertension should be suppressed.

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