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Hyperkalaemia during a general anaesthetic in a 5-year-old domestic short-haired cat.
Aust Vet J
January 2025
Western Australian Veterinary Emergency and Specialty, Success, Western Australia, Australia.
This case report details an incident of hyperkalaemia that developed under general anaesthesia in a domestic cat with no prior health concerns. A 5-year-old male neutered domestic short-haired cat presented for dental extractions and subsequently developed severe bradycardia and electrocardiographic abnormalities during the procedure. Initial treatment with atropine provided limited improvement, and further investigation revealed a serum potassium concentration of 7.
View Article and Find Full Text PDFThe effect of midazolam co-induction on cardiorespiratory variables, myoclonus and etomidate dose requirements in healthy cats.
Vet Anaesth Analg
December 2024
Department of Veterinary Clinical Medicine, College of Veterinary Medicine, University of Illinois, Urbana, IL, USA; Department of Animal Sciences, University of Illinois, Urbana, IL, USA; Division of Nutritional Sciences, University of Illinois, Urbana, IL, USA.
Objective: To evaluate dose requirements of etomidate for endotracheal intubation, with or without midazolam co-induction, and to describe induction quality and associated cardiorespiratory variables in healthy cats.
Study Design: Randomized prospective experimental study.
Animals: A group of 24 adult neutered cats (17 females, seven males).
Motion-Onset Visually Evoked Potentials (VEPs) are Amplified in The Deaf.
J Neurophysiol
January 2025
Department of Physiology, McGill University, Montreal, Quebec H3G 1Y6 Canada.
The loss of a sensory modality triggers a phenomenon known as cross-modal plasticity, where areas of the brain responsible for the lost sensory modality are reorganized and repurposed to the benefit of the remaining modalities. After perinatal or congenital deafness, superior visual motion detection abilities have been psychophysically identified in both humans and cats, and this advantage has been causally demonstrated to be mediated by reorganized auditory cortex. In our study, we investigated visually evoked potentials (VEPs) in response to motion-onset stimuli of varying speeds in both hearing and perinatally deafened cats under light anesthesia.
View Article and Find Full Text PDFPCSK9 exacerbates sevoflurane-induced neuroinflammatory response and apoptosis by up-regulating cGAS-STING signal.
Tissue Cell
January 2025
Anesthesia Surgery Center, People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang Uygur Autonomous Region 830000, China.
Background: Postoperative cognitive dysfunction (POCD) is a postoperative complication that can be induced by anaesthesia. PCSK9 has been shown to have a role in neuronal development and apoptosis. However, PCSK9 has not been studied in sevoflurane-induced POCD-related disorders.
View Article and Find Full Text PDFObjective: This study aimed to evaluate whether pretreatment with gabapentin or alprazolam in cats increases sedation, facilitates intravenous catheter placement (IVCP), or reduces propofol requirements for intubation compared to placebo.
Methods: All cats that participated in this prospective, randomized, blinded, controlled clinical trial were admitted for elective ovariohysterectomy at a veterinary teaching hospital from 2022 to 2023. The cats were healthy, were ≥ 6 months old, and weighed > 3 kg.
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