Background: To study the prevalence of infertility, outcome of pregnancy, and uptake of medical services in a rural population.
Methods: 1000 women aged 45-54 years, randomly selected from the Shropshire FHSA primary care register were sent a postal questionnaire.
Outcome Measures: Response rate, time to pregnancy, pregnancy outcome, medical advice sought, diagnoses, and any treatments.
Results: Of the initial one thousand women, two had to be excluded by age and 142 women were excluded because of wrong address. A total of 728 completed questionnaires were returned leading to a response rate of 85.0%. A total of 74.6% women reported no infertility and 8.1% women were voluntarily sterile. The prevalence of infertility at 12 months was 17.3% and 12.0% at 24 months. The prevalence of primary infertility was 10.6%, of whom 77.9% eventually conceived, and 6.7% had secondary infertility, of whom 71.4% eventually conceived. There were a total of 1680 pregnancies, of which 8.6% ended in spontaneous abortion. The highest proportion of spontaneous abortions (11.4%) was amongst women who had experienced primary infertility. Of all infertile women 51.6% did not seek any advice or treatment and only 34.1% attended for hospital appointments. Ovulatory disorder was the commonest diagnosis. There appeared no association between occupation and infertility, outcome of pregnancy, or uptake of services.
Conclusion: These findings are similar to other epidemiological studies, although in this population the uptake of medical services is low.
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Heliyon
December 2024
Institute of Public Health, College of Medicine and Health Sciences, United Arab Emirates University, Abu Dhabi, United Arab Emirates.
Background: Polycystic ovary syndrome (PCOS) is a significant contributor to female infertility and other various metabolic disorders. This systematic review estimates the prevalence of PCOS among infertile women in the Gulf Cooperation Council (GCC) countries.
Methods: The study searched five databases (PubMed, Embase, CINAHL, Web of Science, and SCOPUS), from their inception to 2022 for observational studies conducted in GCC countries.
Geburtshilfe Frauenheilkd
January 2025
Department of Gynecology, Obstetrics and Reproductive Medicine, Saarland University Hospital, Homburg, Saar, Germany.
Introduction: Identifying non-invasive biomarkers which can predict the outcome of intracytoplasmic sperm injection (ICSI) is crucial, particularly in Germany where the challenges are intensified by the Embryo Protection Act. Recent research has highlighted biomarkers within the epidermal growth factor (EGF) family as central to follicular processes, although their predictive utility remains a subject of debate in the literature. Therefore, the primary objective of this study was to investigate the significance of amphiregulin concentrations in follicular fluid and gene expression in mural granulosa cells on oocyte maturation, fertilization, and embryo quality.
View Article and Find Full Text PDFZygote
January 2025
Molecular Medicine Research Center, Research Institute of Basic Medical Sciences, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
Recently, the World Health Organization recommendation for abstinence time for semen analysis has been challenged in some studies and many of them have supported the advantages of a second short abstinence ejaculation. More evidence is needed to approve this for clinical use. This study aimed to compare the average routine abstinence time (2-7 days) with the short time (1-2 h) on sperm quality based on functional parameters in a population of oligo-astheno-teratozoospermia (OAT) men.
View Article and Find Full Text PDFJ Minim Invasive Gynecol
January 2025
Department of Reproductive Endocrinology, University Hospital Zurich, Frauenklinikstr. 10, 8910, Zurich, Switzerland.
Study Objective: The association between endometriosis and congenital uterine anomalies (CUAs) has been discussed for decades, but existing evidence about this association is scarce. The aim of our study is to evaluate the prevalence of CUAs in women with endometriosis and to identify specific characteristics in women with both CUAs and endometriosis in a large cohort of patients.
Design: This is a retrospective single-center observational study conducted between January 2006 and June 2021.
Afr J Reprod Health
November 2024
National Centre for Technology Management (NACETEM), Obafemi Awolowo University, Ile-Ife, Nigeria.
During the COVID-19 pandemic, Nigeria, like many other countries, implemented a lockdown policy that restricted all movement except for essential services. Access to medical services is a critical component of an effective healthcare system, and without equitable access across genders, improving the overall health outcomes of the population is unlikely to be achieved. This study analyses gender differential in access to medical services and sexual reproductive health services namely, family planning, child health, adult health, pharmacy, emergency care, vaccination, and other medical services during the COVID-19 lockdown in Nigeria, using both descriptive and inferential analytical techniques.
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