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Evolution
January 2025
Centre for Ecological Sciences, Indian Institute of Science, Bengaluru, 560012, India.
Under current climate change patterns, rapidly changing environments can impose strong selection on traits. Costly traits that require heavy investment and strongly affect fitness may be particularly vulnerable to such changes. Despite organisms experiencing dynamic environments, our knowledge of costly trait response is limited as longitudinal studies across generations are rare.
View Article and Find Full Text PDFNucleic Acids Res
January 2025
Université Paris Cité, CNRS, Institut Jacques Monod, F-75013 Paris, France.
Large vertebrate genomes duplicate by activating tens of thousands of DNA replication origins, irregularly spaced along the genome. The spatial and temporal regulation of the replication process is not yet fully understood. To investigate the DNA replication dynamics, we developed a methodology called RepliCorr, which uses the spatial correlation between replication patterns observed on stretched single-molecule DNA obtained by either DNA combing or high-throughput optical mapping.
View Article and Find Full Text PDFInt J Adolesc Med Health
January 2025
Department of Public Health Sciences, Miller School of Medicine, 5452 University of Miami, Miami, FL, USA.
Objectives: This study aimed to examine the relationship between marijuana use and aggression and victimization among Colombian adolescents. We aimed to clarify marijuana's distinct role by comparing different categories of drug use and by considering the order of drug initiation.
Methods: We conducted a secondary analysis of nationally representative cross-sectional data collected from Colombian adolescents in 2016.
Front Neurol
January 2025
National Clinical Research Center for Obstetric & Gynecologic Diseases Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Perinatal depression (PD) is a highly prevalent psychological disorder that has a detrimental effect on infant and maternal physical and mental health, but effective and objective assessment of PD is still insufficient. In recent years, the functional near-infrared spectroscopy (fNIRS) has been acknowledged as an effective non-invasive tool for clinical assessment of depression. This study proposed a free association semantic task (FAST) paradigm for fNIRS-based assessment of PD.
View Article and Find Full Text PDFBMJ Nutr Prev Health
December 2024
Medicine, Nephrology Division, Duke University Medical Center, Durham, North Carolina, USA.
Background: In the early 1940s, before antihypertensive drugs were available, the Rice Diet Programme (RDP) was developed to treat severe hypertension and, later, diabetes and obesity. Despite significant advancements in dietary management for these conditions since then, debates remain regarding the proper guidelines for sodium and macronutrients intakes. The patient care records of RDP offer a unique source of longitudinal examination of a very low sodium (<10 mmol/day), fat, cholesterol and protein diet on blood pressure (BP), other health markers and survival.
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