Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1093/humupd/1.4.324 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Hydroxychloroquine: balancing the need to maintain therapeutic levels with ocular safety: an update.
Curr Opin Rheumatol
May 2018
Division of Rheumatology, Department of Internal Medicine.
Purpose Of Review: Antimalarial drugs including chloroquine, its less toxic quinolone-derivative hydroxychloroquine (HCQ), and quinacrine have become cornerstones in the treatment of autoimmune diseases including systemic lupus, rheumatoid arthritis, sarcoidosis, and Sjogren syndrome; cutaneous disorders, antiphospholipid syndrome, and have recently been employed at higher dioses in oncology. Benefits include anti-inflammatory effects, protection against thrombosis, and improved control of hyperglycemia and hyperlipidemia. In general, both the therapeutic advantages and the toxic effects of the drugs correlate with the dose and the duration of therapy.
View Article and Find Full Text PDFQuinacrine revised.
Hum Reprod Update
July 1995
Department of Physiology and Biophysics, Faculty of Medicine, University of Chile, Santiago, Chile.
[Female non-surgical sterilization: use of endo-uterine quinacrine and betamethasone pellets. Review of the subject: experimental bases--pharmacology--toxicology--efficacy].
Rev Fr Gynecol Obstet
October 1993
Universidad de Chile, Facultad de Medicina Norte, Departamento de Fisiologia y Biofisica, Hôpital Sótero del Rio, Santiago.
Quinacrine produces obstruction of the region of the uterine tube by its fibroblastic granulomatous action. Factors such as the Zn++ and Cu++ content of tubal tissue, as well as the use of anti-prostaglandins, potentialise this action. Two groups of patients were evaluated in this study: Group A--95 women.
View Article and Find Full Text PDFThe early effects of X-rays, vincristine, cyclophosphamide, quinacrine dihydrochloride, cycloheximide, actinomycin D and hydroxyurea on the induction of micronuclei in mouse bone-marrow erythrocytes were studied. A significant increase in the incidence of micronuclei in polychromatic erythrocytes was seen as early as 5 h after a single treatment with vincristine, 6 h after treatment with X-rays and 10 h after treatment with cyclophosphamide. The cell kinetics of the mouse erythropoietic system described by Cole et al.
View Article and Find Full Text PDFThe case of a 10-month-old girl with an extra G-like chromosome is presented. Quinacrine, trypsin-Giemsa, and reverse banding identified the extra chromosome as no. 22.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!