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Guidance on medical physics expert support for nuclear medicine.
Br J Radiol
July 2022
Nuclear Medicine, NHS Grampian, Aberdeen, Representing IPEM, United Kingdom.
The Ionising Radiation (Medical Exposure) Regulations require employers to appoint suitable medical physics experts (MPE) for nuclear medicine services, and they also define the areas where MPEs are required to provide advice and specify matters that they must contribute towards. Applications for employer licences under IR(ME)R require employers to specify the level of MPE support available and if this is provided by onsite MPEs or remotely. Assessment of these applications by the Administration of Radioactive Substances Advisory Committee (ARSAC) has highlighted variability in the levels of MPE support being provided for similar services across the UK.
View Article and Find Full Text PDFEndoplasmic reticulum stress induces cardiac dysfunction through architectural modifications and alteration of mitochondrial function in cardiomyocytes.
Cardiovasc Res
February 2019
Université Versailles St-Quentin, Signalisation et Physiopathologie Cardiovasculaire - UMR-S 1180, Univ. Paris-Sud, INSERM, Université Paris-Saclay, Châtenay-Malabry, France.
Aims: Endoplasmic reticulum (ER) stress has recently emerged as an important mechanism involved in the pathogenesis of cardiovascular diseases. However, the molecular mechanisms by which ER stress leads to cardiac dysfunction remain poorly understood.
Methods And Results: In this study, we evaluated the early cardiac effects of ER stress induced by tunicamycin (TN) in mice.
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