Interest in endoscopic ultrasonography (EUS) has increased during the past fifteen years. Since few years new instrument have been produced, which was equipped with a small curved array transducer mounted in a front of the optic lens. The instrument, which is connected to a Hitachi ultrasonic scanner allows for duplex examination, colour flow imaging, and spectral analysis for measurement of flow velocity. Comparing to the recent unit with mechanical sector transducer, this instrument was equipped with a working channel, which allows to perform biopsies and define the TNM stages. The paper is discussed the evaluation of 55 patient data. This method developing worldwide quickly. By this new EUS technology there is a growing opportunity to substitute other either costly or more invasive methods, and using the TNM classification there is also possible to define whether the patient is suitable for curative surgical intervention or not.
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J Hepatobiliary Pancreat Sci
January 2025
First Department of Internal Medicine, Gifu University Hospital, Gifu, Japan.
Background: Mapping biopsy (MB) can evaluate superficial ductal spread (SDS) through the histopathological diagnosis of cholangiocarcinoma, enabling the selection of an appropriate surgical procedure. This retrospective study evaluated the efficacy of MB using a novel sheath system in distal cholangiocarcinoma (dCCA) cases.
Methods: A total of 199 cholangiocarcinoma cases underwent preoperative diagnosis.
Liver Int
February 2025
Italian Liver Cancer (ITA.LI.CA) Association, Bologna, Italy.
Background And Aims: Presence of active hepatitis C virus (HCV) infection may influence the outcome of patients treated for hepatocellular carcinoma (HCC), although this issue has never been adequately assessed in a large series of patients. The aim of this study was to evaluate whether the presence of active HCV affects the survival of patients treated for HCC.
Methods: This study assessed the outcome of 3123 anti-HCV-positive patients with HCC, subdivided according to the presence of active HCV infection or previous sustained virological response (SVR).
Diagn Pathol
January 2025
Department of Pathology and Laboratory Medicine, Kanazawa Medical University, Ishikawa, 920-0293, Japan.
Background: Hepatoblastoma (HB) is the most common malignant solid tumor of the liver in children and is a fatal disease with a poor prognosis. Therefore, indicators that can be used for the early prediction of the HB prognosis are necessary. Sodium glucose cotransporter 2 (SGLT2) is a glucose transporter protein present in the proximal renal tubules.
View Article and Find Full Text PDFMedicina (Kaunas)
December 2024
Lucid Diagnostics Inc., New York, NY 10017, USA.
Barrett's Esophagus (BE) is the only known precursor for esophageal adenocarcinoma (EAC). Patients with multiple risk factors for BE/EAC are recommended for screening; however, few eligible patients undergo evaluation by endoscopy. EsoGuard (EG) is a commercially available biomarker assay used to analyze esophageal cells collected non-endoscopically with EsoCheck (EC) for the qualitative detection of BE/EAC.
View Article and Find Full Text PDFColorectal Dis
January 2025
Department of Surgery, Yokohama City University, Yokohama, Kanagawa, Japan.
Aim: The risk of lymph node metastasis after endoscopic resection of high-risk T1 colorectal cancer prompts additional resection. However, age and comorbidities are considered in decision-making and some surgeons opt for observation. We compared the long-term outcomes of these approaches with the aim of clarifying the need for additional resection.
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