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A 50-year-old question: Can imidocarb chemoprophylaxis ensure seroconversion for babesiosis in cattle under field conditions?
Vet Parasitol
December 2024
Retired researcher at Instituto de Pesquisas Veterinárias Desidério Finamor (IPVDF), Eldorado do Sul, RS 92990-000, Brazil.
Article Synopsis
- Bovine babesiosis, caused by Babesia bovis and Babesia bigemina, significantly impacts livestock and is often treated with imidocarb in areas lacking vaccines.
- The study involved 15 heifers, with 12 receiving imidocarb and all exposed to ticks to evaluate the development of humoral immunity through seroconversion.
- Results showed that after multiple treatments, a majority of the treated heifers did develop antibodies against the parasites, but not all animals seroconverted, highlighting potential limitations in the effectiveness of the chemoprophylaxis approach.
Effect of a preventive strategic control program, with imidocarb dipropionate, against tick fever agents in dairy calves.
Trop Anim Health Prod
September 2023
Centro de Parasitologia Veterinária, Escola de Veterinária e Zootecnia, Universidade Federal de Goiás, Goiânia, Goiás, Brazil.
Chemoprophylaxis with dipropionate imidocarb (IMD) is a method adopted to prevent cattle tick fever (TF). Sixty weaned dairy heifers (±60 days old), without previous exposure to Rhipicephalus microplus ticks, were housed in Tifton paddocks and were subsequently exposed to R. microplus ticks and monitored up to 315 days old.
View Article and Find Full Text PDFDeveloping Anti- Blood Stage Vaccines: A New Perspective Regarding Synthetic Vaccines.
Int J Mol Sci
March 2023
Molecular Biology and Immunology Department, Fundación Instituto de Inmunología de Colombia (FIDIC), Carrera 50#26-20, Bogotá DC 111321, Colombia.
Bovine babesiosis is caused by the Apicomplexa parasites from the genus . It is one of the most important tick-borne veterinary diseases worldwide; being the species associated with the most severe clinical signs of the disease and causing the greatest economic losses. Many limitations related to chemoprophylaxis and the acaricides control of transmitting vectors have led to the adoption of live attenuated vaccine immunisation against as an alternative control strategy.
View Article and Find Full Text PDFChemoprophylaxis for babesiosis and anaplasmosis in cattle: case report.
Rev Bras Parasitol Vet
January 2021
Programa de Residência Profissional Integrada em Medicina Veterinária, Universidade de Passo Fundo - UPF, Passo Fundo, RS, Brasil.
Cattle tick fever (CTF) causes significant economic losses in the livestock sector. The pathogenic action of the hemoparasites is associated with anemia, weight loss, abortion and reduced productivity, which result with animal death. Programs to prevent CTF involve several procedures, including immunization, chemoprophylaxis and use of ectoparasiticides, together with the vector control in the environment.
View Article and Find Full Text PDFInvestigation into limiting dilution and tick transmissibility phenotypes associated with attenuation of the S24 vaccine strain.
Parasit Vectors
August 2019
Epidemiology, Parasites and Vectors, ARC-Onderstepoort Veterinary Institute, Private Bag X05, Onderstepoort, 0110, South Africa.
Background: Babesia bovis is the causal agent of Asiatic redwater, transmitted by the pandemic tick Rhipicephalus (Boophilus) microplus. Disease control may target the tick vector using acaricides or anti-tick vaccines, or the parasite using chemoprophylaxis or anti-parasite vaccines. Current anti-parasite vaccines comprise live blood vaccines using attenuated B.
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