We measured the changes in cutaneous bilirubin (Br) and serum Br photoisomers in two groups of 5 jaundiced newborn infants treated by intensive phototherapy (IP), one with blue light and the other with green light. Cutaneous Br was measured with a transcutaneous jaundice meter and photoisomers were measured by HPLC. Cutaneous Br decreased in the two groups as soon as IP began, and the skin was completely bleached within 3 h with blue light only. Rebound occurred which was more marked after blue light IP. The main serum photoproduct was the 4Z-15E isomer, which reached a steady-state level within 1 h in both groups, whereas the lumirubin and 4E-15Z Br concentrations were slightly higher after green light IP. These data indicate that blue light is more suitable for IP, although this is not clearly explained by the production of more lumirubin.

Download full-text PDF

Source
http://dx.doi.org/10.1159/000244400DOI Listing

Publication Analysis

Top Keywords

blue light
16
green light
12
changes cutaneous
8
cutaneous bilirubin
8
bilirubin serum
8
intensive phototherapy
8
light
7
blue
5
early changes
4
cutaneous
4

Similar Publications

Public Health.

Alzheimers Dement

December 2024

The Clinical Hospital of Chengdu Brain Science Institute, MOE Key Lab for Neuroinformation, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu, China.

Background: Light therapy has emerged as an effective method for Alzheimer's disease (AD). However, the efficacy on cognitive function in Alzheimer's continuum and factors affecting efficacy have not been established. The study aimed to evaluate the efficacy of 500 nm blue-green light therapy on cognitive function for Alzheimer's continuum, and the main factors affecting light therapy efficacy were analyzed.

View Article and Find Full Text PDF

Background: The retina is a novel biomarker target for examining AD pathology, specifically beta-amyloid (Aβ). Though relationship between retinal Aβ and standard preclinical AD biomarkers (cerebral Aβ PET) remains understudied, retinal inclusion bodies (IB, strongly hypothesized to contain fibrillar Aβ), predict cerebral Aβ load in the anterior cingulate cortex (ACC). This study explored the value of retinal IB as a preclinical AD biomarker, comparing number and surface area (SA) of IB with cerebral Aβ PET.

View Article and Find Full Text PDF

Developing Topics.

Alzheimers Dement

December 2024

IRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna, Italy, Italy.

Background: Current evidence on non-pharmacological treatments in Dementia with Lewy Bodies (DLB) are relatively few and limited by small sample sizes. The goal of this pilot study was to test the efficacy of a new multimodal treatment that combines Tele-Neurorehabilitation and "Bright Light" Therapy (BLT) in a sample of DLB patients.

Method: Eighteen DLB patients (7F; 74.

View Article and Find Full Text PDF

Background: Light-emitting diodes (LEDs) are being used in controlled environments to enhance crop production and pest management with most studies focusing on continuous treatments (applied throughout the entire daytime or nighttime period). Here, we tested the hypothesis that providing tomato plants with timed LED regimes (daily 3-h doses of red, blue, or far-red LED) during the day or at night may affect their traits (leaf reflectance indices, element composition, and phenolic profile), performance of two-spotted spider mites (Tetranychus urticae) (TSSM), and a species of predatory mite (Phytoseiulus persimilis).

Results: Nighttime LED regimes significantly altered leaf element composition: red LED increased K levels, blue LED enhanced Mg levels, and far-red LED enhanced Mn and Cu and reduced Zn levels.

View Article and Find Full Text PDF

Photocurrent Generation by Plant Light-Harvesting Complexes is Enhanced by Lipid-Linked Chromophores in a Self-Assembled Lipid Membrane.

J Phys Chem B

January 2025

Department of Life Science and Applied Chemistry, Graduate School of Engineering, Nagoya Institute of Technology, Gokiso-cho, Showa-ku, Nagoya 466-8555, Japan.

The light-harvesting pigment-protein complex II (LHCII) from plants can be used as a component for biohybrid photovoltaic devices, acting as a photosensitizer to increase the photocurrent generated when devices are illuminated with sunlight. LHCII is effective at photon absorption in the red and blue regions of the visible spectrum, however, it has low absorption in the green region (550-650 nm). Previous studies have shown that synthetic chromophores can be used to fill this spectral gap and transfer additional energy to LHCII, but it was uncertain whether this would translate into an improved performance for photovoltaics.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!