The authors have considered the causes of inability to continue working in tropic climate because of health deterioration for 359 specialists and 19 lethal cases. The main cause of inability to work in tropical climate and primary cause of death was cardiovascular disease. One-third of the cases were due to exacerbation of chronic diseases. The exacerbations occurred more frequently in the most intensive phases of adaptation. Measures which should be taken to prevent breakdown of health in subjects working in tropical conditions are recommended.

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