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Global burden of heart failure in children and adolescents from 1990 to 2019: an analysis from the Global Burden of Disease Study 2019.

World J Pediatr

January 2025

Cardiac Arrhythmia Center, National Center for Cardiovascular Disease, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 167 Beilishi Road, Xicheng District, Beijing, 100037, China.

Background: Heart failure (HF) significantly impacts the cardiovascular health of children and adolescents. This study aims to assess epidemiologic trends in HF across sex, age, region, and time period.

Methods: The number and age-standardized rate (ASR) of prevalence and years lived with disability (YLDs) were derived from the Global Burden of Disease Study 2019.

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Delayed diagnosis of spinal osteoblastoma presenting with radicular pain and scoliosis: A case report.

Int J Surg Case Rep

January 2025

University of Tunis El Manar, Faculty of Medicine of Tunis, 1007, Tunisia; Department of Orthopedic Surgery, Hospital Mongi Slim La Marsa, Tunisia.

Introduction And Importance: Osteoblastoma is a rare benign bone tumor, accounting for 1 % of primary bone tumors, often affecting the spine and sacrum. Accurate diagnosis is essential for appropriate treatment and prognosis.

Case Presentation: A 19-year-old male presented with two years of persistent nocturnal radicular and low back pain unresponsive to anti-inflammatory medications.

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Hospitalization and mortality in children due to COVID-19. A retrospective study from Brazil.

JMIR Pediatr Parent

January 2025

Faculdade de Medicina de Sao Jose do Rio Preto-Brazil, University of Ribeirão Preto, Brazil, Sao Jose do Rio Preto, BR.

Background: Background: COVID-19 is currently one of the most important medical challenges as it affects the entire population, with children being infected as easily as adults.

Objective: The objective of this study was to evaluate the prevalence of mortality in under 19-year-old individuals compared to that of adults.

Methods: This retrospective, observational study analyzed the medical records of all patients diagnosed with COVID-19 by real-time reverse transcription-polymerase chain reaction (RT-PCR) who were hospitalized at Hospital de Base and the Infant and Maternal Hospital of São Jose do Rio Preto, SP, Brazil.

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Differences/disorders of sex development (DSDs) are a diverse group of congenital conditions that result in disagreement between an individual's sex chromosomes, gonads, and/or anatomical sex. The 46, XY DSD group is vast and includes various conditions caused by genetic variants, hormonal imbalances, or abnormal sensitivity to testicular hormones, leading to varying degrees of under-virilization. A 19-year-old phenotypically normal female from Kakamega, Kenya, presented with primary amenorrhea.

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Angiodysplasia is one of the causes of recurrent episodes of lower gastrointestinal (GI) bleeding. Angiodysplasia could be associated with few lesions or multiple diffuse lesions, causing diversity in the clinical presentation of such patients. We report a case of a 19-year-old male presenting with life-threatening gastrointestinal bleeding due to diffuse angiodysplasia of the bowel extending from the jejunum to the sigmoid colon and requiring multiple investigations and management.

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