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Challenges in the management of visual and tactile hallucinations in elderly people.
World J Psychiatry
January 2025
Division of Geriatric Psychiatry, Department of Psychiatry, Changhua Christian Hospital, Changhua 500, Taiwan.
This letter provides a concise review of the pertinent literature on visual and tactile hallucinations in elderly patients. The discussion addresses differential diagnoses and potential underlying mechanisms, as well as the psychopathology associated with tactile hallucinations, and emphasizes the necessity for investigation into the possibility of coexisting delusional infestation (parasitosis). These symptoms frequently manifest in patients with primary psychotic disorders, organic mental disorders, and substance use disorders.
View Article and Find Full Text PDFExploring delusional themes and other symptoms in first episode psychosis: A network analysis over two timepoints.
Psychiatry Res
February 2025
Department of Psychiatry, Faculty of Medicine and Health Sciences, McGill University, 1033 Pine Avenue West, Montreal, QC, , H3A 1A1, Canada; Prevention and Early Intervention Program for Psychosis, Douglas Mental Health University Institute, 6875 Blvd. LaSalle, Montreal, QC, , H4H 1R3, Canada. Electronic address:
Delusions are a defining feature of psychosis and play an important role in the conceptualization and diagnosis of psychotic disorders; however, the particular role that different delusions play in the prognosis of these disorders is not well understood. This study explored relationships between delusions and other symptoms in 674 first episode psychosis (FEP) individuals by comparing symptom networks between baseline and 12 months after intake to an early intervention service. Specifically, we (1) estimated regularized partial correlation networks at baseline and month 12, (2) identified the most central symptoms in each network, (3) identified clusters of highly connected symptoms, and (4) compared networks to examine changes in structure and connectivity.
View Article and Find Full Text PDFPimozide Inhibits Type II but Not Type I Hair Cells in Chicken Embryo and Adult Mouse Vestibular Organs.
Biomedicines
December 2024
Department of Brain and Behavioral Sciences, University of Pavia, 27100 Pavia, Italy.
Background: Pimozide is a conventional antipsychotic drug of the diphenylbutylpiperidine class, widely used for treating schizophrenia and delusional disorders and for managing motor and phonic tics in Tourette's syndrome. Pimozide is known to block dopaminergic D2 receptors and various types of voltage-gated ion channels. Among its side effects, dizziness and imbalance are the most frequently observed, which may imply an effect of the drug on the vestibular sensory receptors, the hair cells.
View Article and Find Full Text PDFSurviving the 2021 heat dome with schizophrenia: A qualitative, interview-based unpacking of risks and vulnerabilities.
Soc Sci Med
December 2024
Department of Psychiatry, Faculty of Medicine, University of British Columbia, B.C. Mental Health and Substance Use Services, Provincial Health Services Authority, Vancouver, BC, Canada.
This study explores the multifaceted challenges experienced by individuals with schizophrenia during extreme heat, highlighting the interplay between individual factors, social dynamics, and environmental influences. Despite making up only 1% of the Canadian population, individuals diagnosed with schizophrenia comprised 16% (n = 97) of the deaths during the 2021 heat dome in Western Canada. However, to date, there exists scant qualitative research that explore the direct experiences and the intricacies of intersecting factors faced by individuals with schizophrenia during extreme heat events.
View Article and Find Full Text PDFTransient Psychotic Relapse Following COVID-19 in a Stable Schizophrenia Patient on Paliperidone Palmitate: A Case Report.
Cureus
November 2024
Psychiatry, Maudsley Health, Al Amal Psychiatric Hospital, Dubai, ARE.
Schizophrenia is a chronic psychiatric disorder marked by severe disturbances in thought, perception, and behavior. Long-acting injectable (LAI) antipsychotics, such as paliperidone, are widely used to promote sustained remission and ensure medication adherence, especially in patients prone to relapse. However, the COVID-19 pandemic has introduced unique challenges, with studies indicating that infections like COVID-19 may exacerbate psychiatric symptoms through neuroinflammatory pathways.
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