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[A lady who is lying crooked].

Ned Tijdschr Geneeskd

January 2025

Anna Ziekenhuis, afd. Interne Geneeskunde, Geldrop.

We present a 78-year-old, unvaccinated woman with a tetanus induced severe opisthotonos, requiring mechanical ventilation. We point out the importance of verifying the vaccination status for older patients born before the early 1950's and patients with a migration background. Additionally, we emphasize on administering appropriate post-exposure prophylaxis.

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Tetanus is a severe neurological condition triggered by the toxin of , resulting in extreme muscle stiffness and spasms. Although vaccination can prevent it, without treatment, tetanus carries a high risk of death due to respiratory failure and autonomic disturbances. This case report describes a 24-year-old Indian male who developed tetanus after branding (a traditional procedure for jaundice in rural India) on his wrist.

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An Unexpected Case of Generalized Tetanus.

Cureus

December 2024

Intensive Care Unit, Unidade Local de Saúde da Região de Aveiro, Aveiro, PRT.

Tetanus is a disease of the nervous system caused by a toxin produced by , an anaerobe found in high concentrations in the soil. The occurrence of tetanus is related to contaminated traumatic wounds, and most patients have had some failure in their immunization. However, there are rare case reports of generalized tetanus in patients with proper vaccination schemes who failed to receive appropriate prophylaxis after high-risk exposure.

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Anti-Tetanus Vaccination Is Associated with Reduced Occurrence and Slower Progression of Parkinson's Disease-A Retrospective Study.

Biomedicines

November 2024

Brain Institute, Tel-Aviv Sourasky Medical Center, Faculty of Medical & Health Sciences, Sagol School of Neurosciences, Tel Aviv University, Tel-Aviv 6997801, Israel.

Parkinson's disease (PD) is a neurodegenerative disorder that progressively damages the autonomic and central nervous systems, leading to hallmark symptoms such as resting tremor, bradykinesia, and rigidity. Despite extensive research, the underlying cause of PD remains unclear, and current treatments are unable to halt the progression of the disease. In this retrospective study, based on historical electronic health records (EHR) from a national health provider covering the period from 2003 to 2023, we investigated the impact of vaccination and medication purchases on PD occurrence and severity.

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Determinants of Neonatal Mortality at a Referral Paediatric Hospital in Angola: A Case-Control Study Using Theoretical Frameworks.

Int J Environ Res Public Health

November 2024

Global Health and Tropical Medicine (GHTM), LA-REAL, Instituto de Higiene e Medicina Tropical (IHMT), Universidade NOVA de Lisboa, 1169-056 Lisboa, Portugal.

Neonatal mortality rates in developing countries are influenced by a complex array of factors. Despite advancements in healthcare, Angola has one of the highest neonatal mortality rates in sub-Saharan Africa, with significant contributors including premature birth, intrapartum events, tetanus, and sepsis. This study, utilizing key theoretical frameworks such as intersectionality, social determinants of health (SDOH), and ecosocial theory, aimed to identify the primary causes and contributing factors of neonatal mortality among infants admitted to the Neonatology Service at DBPH in Luanda from May 2022 to June 2023.

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