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Identifying neural markers of clinical symptom fluctuations is prerequisite to developing more precise brain-targeted treatments in psychiatry. We have recently shown that working memory (WM) in healthy adults is dependent on the rise and fall interplay between alpha/beta and gamma bursts within frontoparietal regions, and that deviations in these patterns lead to WM performance errors. However, it is not known whether such bursting deviations underlie clinically relevant WM-related symptoms or clinical status in individuals with WM deficits.
View Article and Find Full Text PDFDocumented Paternity Despite Azoospermia Post-vasectomy.
Cureus
October 2024
Obstetrics, Orlando Regional Medical Center, Orlando, USA.
Vasectomy is a permanent and safe method of male contraception. One commonly used definition of success is azoospermia in one or two semen analyses after 20 ejaculates after three months. Failure is higher if less than 1.
View Article and Find Full Text PDFAdvances in Estimating Level-1 Phylogenetic Networks from Unrooted SNPs.
J Comput Biol
January 2025
Department of Statistics, University of California at Berkeley, Berkeley, California, USA.
We address the problem of how to estimate a phylogenetic network when given single-nucleotide polymorphisms (i.e., SNPs, or bi-allelic markers that have evolved under the infinite sites assumption).
View Article and Find Full Text PDFGraph-based machine learning model for weight prediction in protein-protein networks.
BMC Bioinformatics
November 2024
ICube, University of Strasbourg, 67412, Illkirch Cedex, France.
Proteins interact with each other in complex ways to perform significant biological functions. These interactions, known as protein-protein interactions (PPIs), can be depicted as a graph where proteins are nodes and their interactions are edges. The development of high-throughput experimental technologies allows for the generation of numerous data which permits increasing the sophistication of PPI models.
View Article and Find Full Text PDFSpatiotemporal Mapping of Auditory Onsets during Speech Production.
J Neurosci
November 2024
Department of Speech, Language, and Hearing Sciences, Moody College of Communication, The University of Texas at Austin, Austin, Texas 78712
The human auditory cortex is organized according to the timing and spectral characteristics of speech sounds during speech perception. During listening, the posterior superior temporal gyrus is organized according to onset responses, which segment acoustic boundaries in speech, and sustained responses, which further process phonological content. When we speak, the auditory system is actively processing the sound of our own voice to detect and correct speech errors in real time.
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