Fifteen patients with various forms of pyelonephritis and chronic cystitis were treated with ofloxacin. The drug was used in the complex antiinflammatory and detoxification therapy and in cases with indicated hemotransfusion. Ofloxacin was administered intravenously during the first days of the treatment with its later oral use. High efficacy of ofloxacin was observed in the patients with acute purulent renal affections accompanied by pyo-intoxication when the treatment was started with the drug parenteral administration.

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