Lipid peroxidation, antioxidant defense and microrheological properties of blood were determined, correlated and compared with clinico-hemodynamic indices in patients with ischemic heart disease (IHD). It is shown that products of lipid peroxidation modify structure and function of red cells and platelets in IHD. A regulatory role of the antioxidant system in metabolism of lipoperoxides and peroxide damage to blood cells in IHD is shown. A pathogenetic implication of correlated changes in the systems of lipid peroxidation and antioxidant defense, microrheological properties of blood in formation of clinical course of IHD is revealed.
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