Phthalic acid esters have been used for its softening and plastification effects as additives to various kinds of products: colours, paintings, glues, cosmetic products, inks, repellents, films, PVC-derived products including medical disposable PVC products. The authors present a basic review of literature on toxicologically important sources including medical disposable products. They refer about the deleterious effects on the mammalian organism, possibilities to replace phthalic acid esters by other softening and plasticizing remedies as well as the use of such kinds of materials, which do not require these additives.
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Environ Int
January 2025
Helmholtz Institute for Metabolic, Obesity and Vascular Research (HI-MAG) of the Helmholtz Centre München at the University of Leipzig Germany; Department of Endocrinology Nephrology Rheumatology University Hospital Leipzig Medical Research Center Leipzig Germany.
Plastic materials are ubiquitous, leading to constant human exposure to plastic additives such as plasticizers. There is growing evidence that plasticizers may contribute to obesity due to their disruptive effects on metabolism. Alternatives like diisononylcyclohexane-1,2-dicarboxylate (DINCH) are replacing traditional phthalates such as di-(2-ethylhexyl) phthalate (DEHP), which are now banned due to their proven harmful health effects.
View Article and Find Full Text PDFJ Hazard Mater
January 2025
College of Environmental and Resource Sciences, Zhejiang University, Hangzhou, Zhejiang 310058, China; Zhejiang Provincial Key Laboratory of Organic Pollution Process and Control, Hangzhou, Zhejiang 310058, China.
The prevalence and persistence of phthalate esters (PAEs) in agricultural soils has garnered global attention. Assessing their potential impacts on crop yield and quality necessitates a thorough understanding of their risks. In this study, we elucidated the carbon flow-dependent mechanisms of the decreased grain quality upon exposure to PAEs through a soil-based rice cultivation experiment.
View Article and Find Full Text PDFJ Org Chem
January 2025
Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China.
The selective oxidative cleavage and functionalization of C(OH)-C bonds in tertiary alcohols harbor immense feasibility in organic synthesis and enable the production of high value-added chemicals from renewable biomass. However, it remains a challenge, owing to the inherent kinetic inertness and thermodynamic stability of C(OH)-C bonds and the lack of C-H. Taking the huge potential and challenge of C(OH)-C bond activation and functionalization into consideration, herein, we show the first example of an inexpensive bifunctional ferric nitrate catalyst for catalytic direct oxidation of structurally distinct tertiary alcohols to esters with environmentally benign molecular oxygen as an oxidant and MeOH as a solvent, without the assistance of any additives.
View Article and Find Full Text PDFJ Oleo Sci
January 2025
College of Marine Biology, Xiamen Ocean Vocational College.
Based on the observation that urea, water, and ethyl esters (EE) can form gypsum-like mixtures, this study explored the feasibility of employing water as a solvent for urea in the urea complexation method to enrich n-3 polyunsaturated fatty acids with docosahexaenoic acid (DHA)-containing ethyl esters (DHA- EE) from Crypthecodinium cohnii as the material. Under the conditions of a urea/DHA-EE ratio of 3, a water/DHA-EE ratio of 0.75, a mixing temperature of 65℃, and a cooling temperature of 20℃, a concentrate containing over 90% DHA was achieved.
View Article and Find Full Text PDFJ Nat Prod
January 2025
School of Pharmacy, Nantong University, 9 Seyuan Road, Nantong 226019, People's Republic of China.
Ten new resin glycosides, controlins I-X (-), were isolated from the seeds of . Their structures were established by spectroscopic analysis as well as by chemical means. Compounds were identified as glycosidic acid methyl esters, considered as artifacts generated via transesterification with MeOH from natural resin glycosides.
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