The results show that irradiation affects both the size of the gonads and the number of germ cells they contain. At stage 64, gonads from irradiated animals were smaller than those from unirradiated ones. The reduced length and thickness of gonads of the test animals were probably due to cell killing. The variation in size of gonads of different test animals and the difference between the left and right ovary of a single individual are indicative of the degree of radiation sensitivity.
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http://dx.doi.org/10.1159/000144834 | DOI Listing |
Vet Med Sci
January 2025
Department of Biochemistry, Faculty of Veterinary Medicine, Erzurum, Turkey.
Background: Isoproterenol (ISO) is a nonselective beta-adrenergic receptor agonist known for its vasodilatory effects. This experiment aims to investigate whether intrauterine ISO administration could alter vascular indices and follicular development in postpartum Holstein cows.
Objectives: The objectives are to evaluate the effects of intrauterine ISO administration on vascular changes and its impact on follicular development compared to placebo groups.
J Clin Endocrinol Metab
January 2025
Marmara University School of Medicine, Department of Pediatric Endocrinology, 34854, Istanbul, Turkey.
Context: Duplications occurring upstream of the SOX9 gene have been identified in a limited subset of patients with 46,XX testicular/ovotesticular differences/disorders of sex development (DSD). However, comprehensive understanding regarding their clinical presentation and diagnosis is limited.
Objective: To gain further insight into the diagnosis of a large cohort of 46,XX individuals with duplications upstream of SOX9.
Toxicol Rep
June 2025
Department of Zoology, University of Kalyani, Nadia, Kalyani, West Bengal 741235, India.
After being exposed, microplastics mostly bioaccumulated in guts and gills of fish, then, through circulation, spread and bioaccumulated in other tissues. Circulatory system of fish is impacted by the microplastic bioaccumulation in their tissues, influencing a number of hematological indices that are connected with immunity, osmotic pressure, blood clotting, molecular transport and fat metabolism. Variables like size, dose, duration, food consumption and species, all affect the bioaccumulation and toxicity of the microplastic, rather than the exposure routes.
View Article and Find Full Text PDFFront Endocrinol (Lausanne)
January 2025
Department of Reproductive Health and Infertility, Zigong Maternal and Child Health Hospital, Zigong, Sichuan, China.
Introduction: The polyspermy rate is a quality control indicator in the embryology laboratory, and factors affecting polyspermy are of great interest. The gonadotropin-releasing hormone (GnRH) antagonist protocol is currently the mainstream protocol in most reproductive centers. This study explored the factors influencing polyspermy in fertilization (IVF) using the GnRH antagonist protocol and considered corresponding improvement measures.
View Article and Find Full Text PDFNat Commun
January 2025
Department of Biology, Institute of Genetics, The Faculty of Mathematics and Natural Sciences, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.
Female reproduction comes at great expense to energy metabolism compensated by extensive organ adaptations including intestinal size. Upon mating, endocrine signals orchestrate a 30% net increase of absorptive epithelium. Mating increases production of the steroid hormone Ecdysone released by the Drosophila ovaries that stimulates intestinal stem cell (ISC) divisions.
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