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Background:  Investigating correlations between clinical, instrumental, and genetic features of primary lymphedema (PL) with the aim to facilitate the diagnosis, the staging, and the management of this subgroup of patients.

Methods:  A prospective observational study was conducted from September 2016 to May 2018, including patients with diagnosis of nonsyndromic PL. All patients underwent a lymphoscintigraphic rest-stress test, an indocyanine green (ICG) lymphographic test, and a genetic test from sputum sample.

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Background: Although genital lymphedema is a challenging disease, its mechanism is unclear. The aim of this study was to identify the lymphatic flow in genital lymphedema and establish a suitable examination for genital lymphedema.

Methods: We injected phytic acid or albumin labeled with Tc at the bilateral first web spaces of the feet of 47 patients for lymphoscintigraphy.

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