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Neuropathology in 1984: a deadly shot into the heart of Europe.
Free Neuropathol
January 2024
Division of Neuropathology and Neurochemistry, Department of Neurology, Medical University Vienna, Vienna, Austria.
Just 40 years ago, Europe was divided into the Eastern communist bloc, which included the Czechoslovak Socialist Republic (ČSSR) and was dominated by the now historical Soviet Union, and the Western bloc comprising democracies such as Austria. The Iron Curtain, a heavily guarded and deadly border zone, separated the two blocs and constrained, in prison style, the populations of the Eastern bloc. The present neuropathological article relates the sad fate of František Faktor, a 33 years-old Czech who was shot by ČSSR border guards when attempting to flee to Austria at the border between and .
View Article and Find Full Text PDFThe association between salivary oxytocin, age, and puberty in children with and without OCD.
Sci Rep
November 2024
Child and Adolescent Mental Health Center, Copenhagen University Hospital - Mental Health Services CPH, Gentofte Hospitalsvej 3A, Hellerup, 2900, Copenhagen, Denmark.
The oxytocin system has been thought to contribute to obsessive-compulsive disorder (OCD). Few studies, only involving adults, have investigated this hypothesis and have found inconsistent results regarding oxytocin system activity and OCD. We investigated whether salivary oxytocin concentrations differed between children and adolescents with and without OCD and qualified our comparative analysis by investigating the possible covariates age, pubertal stage, and sex.
View Article and Find Full Text PDFA case-by-case analysis of EPN and LPP components within a "one-picture-per-emotion-category" protocol.
Psychophysiology
November 2024
Department of Psychology, University of Konstanz, Constance, Germany.
Stimuli encountered in the environment are continuously evaluated according to their affective stimulus significance. Numerous event-related potential studies have shown that the early posterior negativity (EPN) and the late positive potential (LPP) are larger for high than low arousing emotional pictures. The group approach has been recently extended to the study of the individual case.
View Article and Find Full Text PDFRole of human plasma metabolites in prediabetes and type 2 diabetes from the IMI-DIRECT study.
Diabetologia
December 2024
Research Unit of Molecular Epidemiology, Institute of Epidemiology, German Research Center for Environmental Health, Helmholtz Zentrum München, Neuherberg, Germany.
Article Synopsis
- Researchers are studying type 2 diabetes, which happens when there is too much sugar in the blood, to see how certain substances in the body, called metabolites, are connected to it.
- They looked at 3,000 blood samples and analyzed 911 metabolites to find out how these substances relate to blood sugar levels.
- They discovered several metabolites that are different in people with normal blood sugar, those with prediabetes, and those with type 2 diabetes, mainly focusing on specific amino acids and fats.
[Pulmonary hypertension in adults with congenital heart disease in light of the 2022-ESC-PAH guidelines - Part II: Supportive therapy, special situations (pregnancy, contraception, non-cardiac surgery), targeted pharmacotherapy, organ transplantation, special management (shunt lesions, left ventricular disorders, univentricular hearts), interventions, intensive care, follow-up, future perspectives].
Pneumologie
August 2024
Sektion Pädiatrische Kardiologie, Universitätsklinik für Kinder- und Jugendmedizin Ulm, Ulm, Deutschland.
The number of adults with congenital heart defects (CHD) is steadily rising and amounts to approximately 360,000 in Germany. CHD is often associated with pulmonary hypertension (PH), which may develop early in untreated CHD. Despite timely treatment of CHD, PH not infrequently persists or recurs in older age and is associated with significant morbidity and mortality.
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