Adams-DeWeese caval clips have been shown to be effective in preventing pulmonary embolism. However, the use of Teflon clips constitutes a permanent solution for this transient risk. We tested an absorbable caval clip made of currently available synthetic biodegradable polymers in five female beagle dogs. The polymer used was PLA 96 containing 96% L lactic acid and 4% D lactic acid. After placement through a laparotomy, clips were routinely inspected and samples of the material were collected at regular intervals between 3 and 19 months postoperatively. The characteristics of absorption of PLA 96 in the retroperitoneal space were the same as those previously described in the literature. The clip retained its shape, rigidity, and effectiveness for 7 months. Complete degradation of the clip took between 18 and 19 months. Absorption did not cause a major inflammatory reaction and had no thrombogenic effect. Given the small number of animals studied, these results must be considered preliminary.
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http://dx.doi.org/10.1007/BF02000439 | DOI Listing |
J Vasc Surg Cases Innov Tech
June 2024
Division of Vascular Surgery, Department of Surgery, Scripps Clinic, La Jolla, CA.
More than 10 million cases of venous thromboembolisms are reported on an annual basis and are major contributors to morbidity and mortality. Studies have found that ≤90% of pulmonary embolisms originate from the abdominal and lower extremity veins. The mainstay of venous thromboembolism treatment has been, and still continues to be, anticoagulation.
View Article and Find Full Text PDFAnn Vasc Surg
November 2021
Division of Interventional Radiology, Department of Radiological Sciences, UCLA David Geffen School of Medicine, Los Angeles, CA; Division of Interventional Radiology, Department of Radiology, Mater Misericordiae University Hospital, Dublin 7, Ireland.
Percutaneous mitral valve (MV) repair using MitraClip requires large-caliber venous access. We describe a patient with a ligated inferior vena cava due to an Adams-DeWeese clip placed 50 years prior, who had progressive shortness of breath and lower extremity symptoms secondary to severe mitral regurgitation and chronic iliocaval deep venous thrombosis. Due to comorbidities, MitraClip was recommended over surgery for MV repair.
View Article and Find Full Text PDFAnn Vasc Surg
November 1996
Clinique Chirurgicale, Hôpital Cochin, Paris, France.
Adams-DeWeese caval clips have been shown to be effective in preventing pulmonary embolism. However, the use of Teflon clips constitutes a permanent solution for this transient risk. We tested an absorbable caval clip made of currently available synthetic biodegradable polymers in five female beagle dogs.
View Article and Find Full Text PDFAlthough anticoagulation remains the treatment of choice for acute pulmonary embolism, vena caval interruption represents an alternative for patients with contraindications and complications or in whom anticoagulation fails. The purpose of this study was to evaluate the effectiveness and safety of two types of caval interruption devices: the original stainless steel Greenfield filter and the Adams-DeWeese clip. Emphasis has been placed on maintaining caval patency with filters and clips and the patency of the femoral vein vs.
View Article and Find Full Text PDFPulmonary embolism is frequently fatal and its treatment and prevention are of vital importance. Curative therapy depends mainly on the use of heparin or urokinase, embolectomy under extracorporeal circulation being reserved for the most severe cases, and Trendelenburg's operation limited in its application at the present time. Prevention of pulmonary embolism is the principal problem and involves, apart from the use of anticoagulants, insertion of a caval clamp by means of a Adams Deweese clip whenever possible, or by the use of an endoluminal filter.
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