The regulatory subunit type II (RII) of cAMP-dependent protein kinase purified from human brain was represented by two proteins with apparent molecular masses of 51-52 kD and 54 kD. Dephosphorylation of human RII containing 3 mol phosphate/mol protein did not change the electrophoretic pattern. One-dimensional peptide mapping of 51-52 kD and 54 kD proteins after digestion with St. aureus V8 protease evidenced to their being distinct proteins. The data obtained permit to assume that human RII of neural type is represented by two isoforms.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1080/15216549600201793 | DOI Listing |
Publication Analysis
Top Keywords
regulatory subunit
8
camp-dependent protein
8
protein kinase
8
human brain
8
human rii
8
properties regulatory
4
subunit camp-dependent
4
kinase type
4
human
4
type human
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!