Intussusception is uncommon in infants with a colostomy. The authors present the first documented case of intussusception in an infant with a colostomy in which pneumatic reduction was achieved via the stomal opening. The inflated balloon of a Foley catheter was plugged against the stoma at skin level and a tight seal was obtained. Successful reduction was achieved without any adverse effects to the patient.
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http://dx.doi.org/10.1016/s0022-3468(96)90056-1 | DOI Listing |
Biomacromolecules
January 2025
Polymer Research Centre and Centre for Advanced Functional Materials, Department of Chemical Sciences, Indian Institute of Science Education and Research Kolkata, Nadia, Mohanpur 741246, West Bengal, India.
The present investigation aims to develop a reactive oxygen species (ROS) and esterase-responsive biodegradable mannosylated polyurethane to effectively deliver the encapsulated antileishmanial drug amphotericin B (AmB) selectively to infected macrophage cells. Owing to suitable amphiphilic balance, the as-synthesized glycosylated polyurethane () with aryl boronic ester-based diol () moiety as ROS-trigger, water-soluble mannose pendants, and fluorescent 4,4-difluoro-4-bora-3a,4a-diaza--indacene (BODIPY) chain ends for bioimaging formed nanoaggregates in an aqueous medium as confirmed by H NMR spectroscopy, dynamic light scattering (DLS), field emission scanning electron microscopy (FESEM), transmission electron microscopy (TEM), and critical aggregation concentration (CAC) measurements. Aided by two endogenous stimuli present in phagolysosome, ROS and esterase, AmB-encapsulated polymeric nanoaggregates as drug delivery vehicles achieved an efficient reduction of both and intracellular amastigote burden compared to the free AmB.
View Article and Find Full Text PDFPLoS One
January 2025
School of Physical Education, Jinjiang College, Sichuan University, Chengdu, Sichuan Province, People's Republic of China.
In athletes' competitions and daily training, in order to further strengthen the athletes' sports level, it is usually necessary to analyze the athletes' sports actions at a specific moment, in which it is especially important to quickly and accurately identify the categories and positions of the athletes, sports equipment, field boundaries and other targets in the sports scene. However, the existing detection methods failed to achieve better detection results, and the analysis found that the reasons for this phenomenon mainly lie in the loss of temporal information, multi-targeting, target overlap, and coupling of regression and classification tasks, which makes it more difficult for these network models to adapt to the detection task in this scenario. Based on this, we propose for the first time a supervised object detection method for scenarios in the field of motion management.
View Article and Find Full Text PDFThis study intends to optimize the carbon footprint management model of power enterprises through artificial intelligence (AI) technology to help the scientific formulation of carbon emission reduction strategies. Firstly, a carbon footprint calculation model based on big data and AI is established, and then machine learning algorithm is used to deeply mine the carbon emission data of power enterprises to identify the main influencing factors and emission reduction opportunities. Finally, the driver-state-response (DSR) model is used to evaluate the carbon audit of the power industry and comprehensively analyze the effect of carbon emission reduction.
View Article and Find Full Text PDFACS Appl Mater Interfaces
January 2025
Physical & Materials Chemistry Division, CSIR-National Chemical Laboratory, Pune, Maharashtra 411008, India.
This work aims to deal with the challenges associated with designing complementary bifunctional electrocatalysts and a separator/membrane that enables rechargeable zinc-air batteries (RZABs) with nearly solid-state operability. This solid-state RZAB was accomplished by integrating a bifunctional electrocatalyst based on Ru-RuO interface nanoparticles supported on nitrogen-doped (N-doped) graphene (Ru-RuO/NGr) and a dual-doped poly(acrylic acid) hydrogel (d-PAA) electrolyte soaked in KOH with sodium stannate additive. The catalyst shows enhanced activity and stability toward the two oxygen reactions, i.
View Article and Find Full Text PDFCurr Atheroscler Rep
January 2025
Carbohydrate and Lipid Metabolism Research Unit, Department of Medicine, University of the Witwatersrand, Johannesburg, South Africa.
Purpose Of Review: Homozygous familial hypercholesterolaemia (HoFH) is characterized by marked elevation of low-density lipoprotein cholesterol (LDLC) and premature atherosclerotic cardiovascular disease. This is a review of novel pharmacological therapies to lower LDLC in patients with HoFH.
Recent Findings: Novel therapies can be broadly divided by whether their efficacy is dependent or independent of residual low-density lipoprotein receptor (LDLR) function.
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