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Enhanced Mechanical Properties in Bulk Nanograined Ni with High-Density Fivefold Twins.

Small

January 2025

Shenyang National Laboratory for Materials Science, Institute of Metal Research, Chinese Academy of Sciences, Shenyang, 110016, China.

Fivefold twins are extensively present in nanoparticles and nanowires, enhancing their performance in physical, chemical, and mechanical properties. However, a deep insight into the correlation between mechanical properties and fivefold twins in bulk nanograined materials is lacking due to synthesis difficulties. Here, a bulk fivefold-twinned nanograined Ni is synthesized via electrodeposition.

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This work involves the preparation of dual surrogate-imprinted polymers (D-MIPs) for the capture of SARS-CoV-2. To achieve this goal, an innovative and novel dual imprinting approach using carboxylated-polystyrene (PS-COOH) nanoparticles with a diameter of 100 nm and a SARS-CoV-2 Spike-derived peptide was carried out at the surface of amine-functionalized silica (PS-NH) microspheres with a diameter of 500 nm. Firstly, PS-COOH nanoparticles with the same size and spherical shape as the SARS-CoV-2 virus were employed to form hemispherical indentations (HI) at the surface of the PS-NH microspheres (obtaining dummy particle-imprinted polymers, HI-MIPs).

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Advances in magnetic nanoparticles for molecular medicine.

Chem Commun (Camb)

January 2025

F. Joseph Halcomb III, M. D. Department of Biomedical Engineering, University of Kentucky, Lexington, Kentucky 40536, USA.

Magnetic nanoparticles (MNPs) are highly versatile nanomaterials in nanomedicine, owing to their diverse magnetic properties, which can be tailored through variations in size, shape, composition, and exposure to inductive magnetic fields. Over four decades of research have led to the clinical approval or ongoing trials of several MNP formulations, fueling continued innovation. Beyond traditional applications in drug delivery, imaging, and cancer hyperthermia, MNPs have increasingly advanced into molecular medicine.

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Skin represents an effective barrier against the penetration of external agents into the human body. Nevertheless, recent research has shown that small particles, especially in the nanosized range, can not only penetrate through the skin but also work as vectors to transport active molecules such as contrast agents or drugs. This knowledge has opened new perspectives on nanomedicine and controlled drug delivery.

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PbZrTiO cubes with tunable sizes and cuboids have been hydrothermally synthesized. PbZrTiO cubes with three different Zr : Ti atomic percentages were also prepared. Analysis of synchrotron X-ray diffraction (XRD) patterns reveals the presence of two lattice components for these samples.

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